Bull Hosp Jt Dis (2013). 2022 Jun;80(2):228-233.
Bulletin of the Hospital for Joint Diseases 2022;80(2):228-33228 Mahmood B, Golub IJ, Ashraf AM, Ng MK, Vakharia RM, Choueka J. Risk factors for infections following open reduction and internal fixation for distal radius fractures: an analysis of the medicare claims database. Bull Hosp Jt Dis. 2022;80(2):228-33. Abstract Background: Infections following open reduction and internal fixation (ORIF) of distal radius fractures (DRFs) are associated with worse outcomes and increasing health care costs. The purpose of this study was to utilize a nationwide administrative claims database to compare patient demo- graphics of patients who did and did not develop infections and identify patient-related risk factors for postoperative infections.
Using the PearlDiver database, the 100% Medicare Files from 2005 to 2014 were queried. Patients undergoing ORIF for DRF were identified using Current Procedural Terminology (CPT) codes. Inclusion for the study group consisted of patients who developed infection within 90 days after the procedure and were identified us- ing CPT and International Classification of Disease, Ninth Revision (ICD-9) codes. Multivariable binomial logistic regression analyses were performed to calculate the odds (OR) of certain patient comorbidities and their association with infection following ORIF of DRFs. A p-value less than 0.002 was considered statistically significant after Bonfer- roni correction.
The query yielded 132,650 patients within the study, 456 who developed surgical site infections (SSI) and 132,194 who did not. Surgical site infections were more commonly found in certain demographics, such as patients under the age of 65 (26.75 vs. 14.73%) and in males (20.83 vs. 14.15%). Multivariate regression analysis further highlighted that certain comorbidities increased odds for infections within 90-days following ORIF for distal radius fractures and those included: morbid obesity (OR: 2.06, p < 0.0001), depression (OR: 1.92, p = 0.0002), and pathologic weight loss (OR: 1.49, p = 0.001).
The study found statistically significant dif- ferences between patients who developed and did not develop infection. These findings may help orthopedic surgeons to educate certain high-risk patients of the potential complica- tions that may occur following surgery.
切开复位内固定(ORIF)治疗桡骨远端骨折(DRF)后感染与更差的预后和增加的医疗保健成本相关。本研究的目的是利用全国性行政索赔数据库比较发生和未发生感染的患者的人口统计学特征,并确定与术后感染相关的患者相关危险因素。
使用 PearlDiver 数据库,从 2005 年至 2014 年查询了 Medicare 100%档案。使用当前程序术语(CPT)代码识别接受 DRF ORIF 的患者。研究组的纳入标准为术后 90 天内发生感染的患者,并使用 CPT 和国际疾病分类,第 9 版(ICD-9)代码进行识别。进行多变量二项逻辑回归分析以计算某些患者合并症的优势比(OR)及其与 DRF ORIF 后感染的关系。Bonferroni 校正后 p 值小于 0.002 被认为具有统计学意义。
查询产生了 132650 名符合研究条件的患者,其中 456 名发生手术部位感染(SSI),132194 名未发生。在某些人群中,如年龄在 65 岁以下的患者(26.75%比 14.73%)和男性(20.83%比 14.15%),更常发现手术部位感染。多变量回归分析进一步强调,某些合并症增加了 90 天内接受 ORIF 治疗的桡骨远端骨折后感染的几率,包括:病态肥胖(OR:2.06,p < 0.0001)、抑郁(OR:1.92,p = 0.0002)和病理性体重减轻(OR:1.49,p = 0.001)。
该研究发现发生和未发生感染的患者之间存在统计学显著差异。这些发现可能有助于骨科医生向某些高危患者教育手术后可能发生的潜在并发症。