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微生物孢子遗传标记技术,一种用于中药溯源系统的潜在技术。

Microbial spore genetic marker technology, a potential technology for traditional Chinese medicine traceability system.

作者信息

Zhao Dazhong, Tian Zunzhe, Cai Jing, He Juan

机构信息

School of Ecology and Environment, Northwestern Polytechnical University, Xi'an, 710072, China.

出版信息

Chin Med. 2022 May 28;17(1):61. doi: 10.1186/s13020-022-00620-9.

DOI:10.1186/s13020-022-00620-9
PMID:35643582
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9148530/
Abstract

Traditional Chinese medicine (TCM) has a long history, rich clinical experience, and unique advantages in the prevention and treatment of diseases. The quality and safety of Chinese medicinal materials (CMMs) directly affect the clinical efficacy and development of the TCM industry. However, confused provenance, counterfeiting and adulteration of CMMs hinder the acceptance of its therapeutic benefits in modern society. Therefore, the establishment and improvement of a TCM traceability system would be conducive to the transparency of the CMMs production, distribution, and circulation, thereby improving drug safety and promoting industry development. This review discusses the challenges faced in the development of TCM traceability system, the technologies currently available for tracing CMMs, and the potential application of Barcoded Microbial Spores (BMS) to improve CMMs origin traceability and TCM traceability systems.

摘要

中医历史悠久,临床经验丰富,在疾病防治方面具有独特优势。中药材的质量和安全性直接影响中医临床疗效和中医药产业发展。然而,中药材来源混乱、假冒伪劣现象阻碍了其治疗效果在现代社会被认可。因此,建立和完善中药追溯体系有助于提高中药材生产、销售和流通的透明度,从而提高药品安全性,促进行业发展。本文综述了中药追溯体系发展面临的挑战、目前可用于追溯中药材的技术,以及条形码微生物孢子(BMS)在提高中药材产地追溯和中药追溯体系方面的潜在应用。

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Chin Med. 2022 May 28;17(1):61. doi: 10.1186/s13020-022-00620-9.
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2
Comparison of Geographical Traceability of Wild and Cultivated with Different Data Fusion Approaches.不同数据融合方法下野生与栽培品种地理溯源性的比较。
J Anal Methods Chem. 2021 Jul 21;2021:5818999. doi: 10.1155/2021/5818999. eCollection 2021.
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Rapid and robust assembly and decoding of molecular tags with DNA-based nanopore signatures.
基于 DNA 纳米孔特征的分子标签的快速和稳健组装与解码。
Nat Commun. 2020 Nov 3;11(1):5454. doi: 10.1038/s41467-020-19151-8.
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Barcoded microbial system for high-resolution object provenance.条形码微生物系统用于高分辨率物体溯源。
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Assesment of Adulterated Traditional Chinese Medicines in China: 2003-2017.中国掺假中药的评估:2003 - 2017年
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Quality evaluation of traditional Chinese medicines based on fingerprinting.基于指纹图谱的中药质量评价。
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