[不同蛋白质摄入方案下维持血液蛋白质组成的机制]
[Mechanism for maintaining blood protein composition with various protein regimens].
作者信息
Gapparov M M, Charochkina L L, Mal'tsev G Iu, Sokolov A I
出版信息
Vopr Pitan. 1987 Jan-Feb(1):31-4.
The study of the blood plasma protein content, turnover constant and half-life of albumin, fibrinogen and the total fraction of IgG + transferrin, was conducted in 70 male Wistar rats which received rations containing 4, 8, 12, 18 and 36% protein (casein), during a month. The total serum protein content and the proteins assayed in the blood plasma were not reliably changed in relation to the protein level in the animals' ration. It was found that the half-life of the proteins studied increased with the lowering of the protein content in the ration. It is suggested that the increase of the blood plasma protein half-life is one of the mechanisms of maintaining stable blood plasma protein composition in case of insufficient protein content in the food ration.
对70只雄性Wistar大鼠进行了研究，这些大鼠在一个月内食用含有4%、8%、12%、18%和36%蛋白质（酪蛋白）的日粮，检测了血浆中白蛋白、纤维蛋白原以及IgG + 转铁蛋白总组分的蛋白质含量、周转常数和半衰期。总血清蛋白含量以及血浆中检测的蛋白质与动物日粮中的蛋白质水平并无可靠的变化关系。研究发现，所研究蛋白质的半衰期会随着日粮中蛋白质含量的降低而增加。研究表明，血浆蛋白半衰期的增加是在日粮蛋白质含量不足时维持血浆蛋白组成稳定的机制之一。
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