Department of Occupational and Environmental Health Sciences, Peking University School of Public Health, Beijing, China.
Department of Occupational and Environmental Health Sciences, Peking University School of Public Health, Beijing, China; Environmental Research Group, Faculty of Medicine, School of Public Health, Imperial College London, London, UK.
Environ Res. 2022 Sep;212(Pt D):113558. doi: 10.1016/j.envres.2022.113558. Epub 2022 May 27.
Greenness is an emerging modifiable environmental factor of high blood pressure and hypertension. However, current evidence is inconsistent, and high-quality studies are urgently needed, especially in developing country with high disease burden of hypertension.
A longitudinal study was designed and 9,649 participants (aged ≥45 years) with 22,854 number of visits among three waves between 2011 and 2015 were included based on the China Health and Retirement Longitudinal Study. Long term greenness exposure was assessed by annual normalized difference vegetation index (NDVI). Linear and generalized linear mixed effect models were used to estimate the associations between greenness and blood exposure level and hypertension risk, respectively.
The median NDVI level was 0.51, with a range from 0.09 to 0.74. An interquartile range (0.15) increase in NDVI was related to 1.05 mmHg reduction (95% CI: -1.65, -0.45) of systolic blood pressure, 0.72 mmHg reduction (95% CI: -1.06, -0.37) of diastolic blood pressure, and 12% (95% CI: 1%, 22%) lower odds of hypertension risk. The association of greenness and blood pressure was significantly stronger in the younger (<60 years) than in the older (≥60 years), and partially mediated by body mass index.
These findings highlight the protective effect of greenness on blood pressure and hypertension in Chines middle-aged and elderly population, especially in the younger (<60 years), and suggest policy makers to take greenness level into special consideration in the process of urbanization.
绿色环境是高血压和高血压的一个新的可调节环境因素。然而,目前的证据并不一致,迫切需要高质量的研究,特别是在高血压疾病负担高的发展中国家。
本研究设计了一项纵向研究,根据中国健康与退休纵向研究,纳入了 2011 年至 2015 年三波之间的 9649 名参与者(年龄≥45 岁),共 22854 次就诊。长期绿色暴露水平通过年标准化差异植被指数(NDVI)进行评估。线性和广义线性混合效应模型分别用于估计绿色环境与血压暴露水平和高血压风险之间的关系。
NDVI 中位数水平为 0.51,范围为 0.09-0.74。NDVI 增加一个四分位距(0.15)与收缩压降低 1.05mmHg(95%CI:-1.65,-0.45)、舒张压降低 0.72mmHg(95%CI:-1.06,-0.37)和高血压风险降低 12%(95%CI:1%,22%)相关。在年龄较小(<60 岁)的人群中,绿色环境与血压的相关性明显强于年龄较大(≥60 岁)的人群,且部分通过体重指数介导。
这些发现强调了绿色环境对中国中老年人群血压和高血压的保护作用,特别是在年龄较小(<60 岁)的人群中,建议决策者在城市化进程中特别考虑绿色环境水平。