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[非精原细胞瘤性睾丸癌I期行淋巴结清扫术是否仍合理?]

[Is lymphadenectomy in stage I of non-seminomatous testicular cancer still justified?].

作者信息

Höltl W, Kosak D, Pont J, Hruby W

出版信息

Wien Klin Wochenschr. 1987 Jan 23;99(2):60-3.

PMID:3564488
Abstract

Testicular cancer is the tumour of the male genital tract which is most easily and successfully treated today. This very circumstance dictates that for ethical reasons we are more bound than ever to prevent unnecessary diagnostic and therapeutic procedures in these young patients. They should receive only the maximum necessary and not the maximum possible therapy. The difference between these two critical concepts determines the extent of treatment morbidity. Retroperitoneal lymphadenectomy (RLA) is only a diagnostic procedure in approximately 85% of cases. This is the reason for critically reviewing the necessity of this investigation in early non-seminomatous cancer of the testes. The prognostic impact of vascular invasion by the primary tumour is demonstrated in a retrospective study of 86 pathohistological specimens of germ cell tumours. We suggest the inclusion of vascular invasion basically as criterion for any prospective "wait and see" protocol in early non-seminomatous germ cell tumours.

摘要

睾丸癌是男性生殖道中目前最易于且最成功治疗的肿瘤。正是这种情况决定了,出于伦理原因,我们比以往任何时候都更有责任避免在这些年轻患者中进行不必要的诊断和治疗程序。他们应仅接受最大必要而非最大可能的治疗。这两个关键概念之间的差异决定了治疗的发病率。在大约85%的病例中,腹膜后淋巴结清扫术(RLA)仅作为一种诊断程序。这就是严格审查该检查对于早期非精原细胞瘤性睾丸癌必要性的原因。对86份生殖细胞肿瘤病理组织学标本的回顾性研究表明了原发性肿瘤血管侵犯的预后影响。我们建议,在早期非精原细胞性生殖细胞肿瘤的任何前瞻性“观察等待”方案中,基本应将血管侵犯纳入标准。

相似文献

1
[Is lymphadenectomy in stage I of non-seminomatous testicular cancer still justified?].[非精原细胞瘤性睾丸癌I期行淋巴结清扫术是否仍合理?]
Wien Klin Wochenschr. 1987 Jan 23;99(2):60-3.
2
[Urologic treatment of testicular germ cell cancer].睾丸生殖细胞癌的泌尿外科治疗
Arch Esp Urol. 2002 Oct;55(8):927-36.
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[Modified retroperitoneal lymphadenectomy in non-seminomatous stage I, IIa and IIb testicular tumors].[非精原细胞瘤 I 期、IIa 期和 IIb 期睾丸肿瘤的改良腹膜后淋巴结清扫术]
Urologe A. 1995 Nov;34(6):444-8.
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[Effect of biological prognostic factors on therapy of non-seminomatous stage I testicular tumors--an assessment of the current status].[生物学预后因素对I期非精原细胞瘤性睾丸肿瘤治疗的影响——现状评估]
Urologe A. 1996 Jan;35(1):35-45.
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[Is risk-oriented therapy in stage I non-seminoma tumor advisable?].
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[Delayed retroperitoneal lymph node excision in treatment of advanced non-seminomatous germinal cell tumors. I. Intraoperative findings in marker converted tumor].[晚期非精原细胞性生殖细胞肿瘤的延迟性腹膜后淋巴结切除术。I. 标志物转换型肿瘤的术中发现]
Urologe A. 1993 May;32(3):189-93.
7
Lymphadenectomy for testicular carcinoma.睾丸癌淋巴结清扫术
Can J Surg. 1982 May;25(3):262-6.
8
[Modified retroperitoneal lymph node excision in testicular tumors. Anatomy, surgical technique and results].
Urologe A. 1993 May;32(3):194-200.
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Complications of primary nerve sparing retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumors of the testis: experience of the German Testicular Cancer Study Group.睾丸临床I期非精原细胞性生殖细胞肿瘤保留神经的腹膜后淋巴结清扫术的并发症:德国睾丸癌研究组的经验
J Urol. 2003 May;169(5):1710-4. doi: 10.1097/01.ju.0000060960.18092.54.
10
[Results of treatment following stage-dependent therapy of non-seminomatous testicular tumors].[非精原细胞瘤性睾丸肿瘤分期依赖性治疗后的治疗结果]
Z Urol Nephrol. 1987 Oct;80(10):587-93.