Department of Otorhinolaryngology, Speech and Hearing Centre, Erasmus University Medical Center, Rotterdam; The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands.
Department of Otorhinolaryngology, University Medical Center Utrecht, Utrecht, The Netherlands.
Noise Health. 2022 Jan-Mar;24(112):20-26. doi: 10.4103/nah.nah_38_21.
Adolescents may be at risk of noise-induced hearing loss due to recreational sound. The aim of this study was to examine the role of distortion product otoacoustic emissions (DPOAEs) in screening for early stages of high-frequency loss such as can be observed in noise-induced hearing loss.
This cross-sectional study was embedded within Generation R, an ongoing prospective birth cohort study in Rotterdam, The Netherlands. Data were collected from April 2016 to September 2019.
A total of 3456 adolescents with a mean age of 13 years and 8 months old (standard deviation ± 5 months) were included. Pure-tone thresholds were measured in a sound-treated booth. DPOAEs were recorded using an ILO V6 analyzer with primary levels of 65/55 dB SPL and frequency ratio f/f of 1.22. Subjects had normal middle ear function at the time of assessment, based on tympanometry results.
Measurements in 6065 ears showed that DPOAE levels tend to decrease with increasing pure-tone thresholds. However, the intersubject variability of DPOAE levels in ears with the same threshold was large. DPOAE levels could reasonably identify early stages of high-frequency hearing loss.
The findings of present study indicate that DPOAE measurements can potentially be used for adolescents hearing screening in the high frequencies. Future research is needed to optimize test performance.
由于娱乐性噪音，青少年可能有患噪声性听力损失的风险。本研究旨在探讨畸变产物耳声发射（DPOAE）在筛查高频损失早期阶段（如噪声性听力损失中观察到的）中的作用。
本横断面研究嵌入于荷兰鹿特丹进行的一项正在进行的前瞻性出生队列研究 Generation R 中。数据收集于 2016 年 4 月至 2019 年 9 月。
共纳入 3456 名平均年龄为 13 岁 8 个月（标准差±5 个月）的青少年。纯音阈值在隔音室内进行测量。使用 ILO V6 分析仪记录 DPOAE，初级水平为 65/55 dB SPL，频率比 f/f 为 1.22。根据鼓室图结果，评估时所有受试者中耳功能正常。
对 6065 只耳朵的测量结果表明，DPOAE 水平随着纯音阈值的升高而降低。然而，具有相同阈值的耳朵中 DPOAE 水平的个体间变异性较大。DPOAE 水平可以合理地识别高频听力损失的早期阶段。
本研究结果表明，DPOAE 测量可能可用于青少年高频听力筛查。需要进一步的研究来优化测试性能。
