Attias J, Bresloff I, Reshef I, Horowitz G, Furman V
Institute for Clinical Neurophysiology and Audiology, Schneider Children's Medical Center of Israel, Petach Tikva.
Br J Audiol. 1998 Feb;32(1):39-46. doi: 10.3109/03005364000000049.
This study assessed the clinical efficacy of screening for noise induced hearing loss (NIHL) with distortion product otoacoustic emissions (DPOAE). DPOAEs were recorded from 76 military personnel (137 ears) aged between 17 and 41 years in response to equilevel 70 dB SPL primary stimulating tones. The 2f1-f2 DPOAE levels were correlated with audiometric thresholds at frequencies close to f2. Ears with normal audiograms, but with a history of military noise exposure, had DPOAEs that were significantly decreased in amplitude as compared to the ears of normal hearing non-exposed to noise subjects. These ears also had an increased absence of DPOAEs as compared with the ears of the normal hearing non-exposed to noise subjects. Although, in general, the DPOAE amplitudes and spectral frequency ranges reflected the audiometric NIHL configurations, in a number of cases DPOAEs were present for hearing losses up to 75 dB HL. As a consequence, DPOAEs correlated moderately and negatively with the audiometric thresholds. Applying test criteria designed to logically reflect NIHL, DPOAE sensitivity and specificity levels ranged between 0.51-0.90 and 0.63-0.25, respectively. These findings indicate that DPOAEs, recorded and analysed as described, are not sufficiently sensitive to serve as a single test to identify NIHL.
本研究评估了用畸变产物耳声发射(DPOAE)筛查噪声性听力损失(NIHL)的临床疗效。对76名年龄在17至41岁之间的军人(137只耳)记录DPOAE,以响应等强度70 dB SPL的初级刺激音。2f1-f2 DPOAE水平与接近f2频率处的听力阈值相关。听力图正常但有军事噪声暴露史的耳,其DPOAE幅度与未暴露于噪声的正常听力者的耳相比显著降低。与未暴露于噪声的正常听力者的耳相比,这些耳中DPOAE缺失也增加。尽管总体上DPOAE幅度和频谱频率范围反映了听力测量的NIHL形态,但在一些情况下,听力损失高达75 dB HL时仍存在DPOAE。因此,DPOAE与听力阈值呈中度负相关。应用旨在合理反映NIHL的测试标准时,DPOAE的敏感性和特异性水平分别在0.51 - 0.90和0.63 - 0.25之间。这些发现表明,按所述记录和分析的DPOAE作为识别NIHL的单一测试不够敏感。