Chavda Vishal, Chaurasia Bipin, Fiorindi Alessandro, Umana Giuseppe E, Lu Bingwei, Montemurro Nicola
Department of Pathology, Stanford School of Medicine, Stanford University Medical Center, San Francisco, CA 94305, USA.
Department of Neurosurgery, Bhawani Hospital and Research Center, Birgunj 44300, Nepal.
Neurol Int. 2022 Apr 24;14(2):391-405. doi: 10.3390/neurolint14020032.
Stroke is a fatal morbidity that needs emergency medical admission and immediate medical attention. COVID-19 ischemic brain damage is closely associated with common neurological symptoms, which are extremely difficult to treat medically, and risk factors. We performed literature research about COVID-19 and ischemia in , and for this current narrative review. We discovered parallel manifestations of SARS-CoV-19 infection and brain ischemia risk factors. In published papers, we discovered a similar but complex pathophysiology of SARS-CoV-2 infection and stroke pathology. A patient with other systemic co-morbidities, such as diabetes, hypertension, or any respiratory disease, has a fatal combination in intensive care management when infected with SARS-CoV-19. Furthermore, due to their shared risk factors, COVID-19 and stroke are a lethal combination for medical management to treat. In this review, we discuss shared pathophysiology, adjuvant risk factors, challenges, and advancements in stroke-associated COVID-19 therapeutics.
中风是一种致命的疾病,需要紧急住院治疗并立即接受医疗护理。新型冠状病毒肺炎(COVID-19)所致的缺血性脑损伤与常见的神经症状密切相关,这些症状极难通过药物治疗,且与风险因素有关。我们针对此次叙述性综述,检索了关于COVID-19和缺血方面在[具体数据库1]、[具体数据库2]及[具体数据库3]中的文献。我们发现了严重急性呼吸综合征冠状病毒1(SARS-CoV-19)感染与脑缺血风险因素的平行表现。在已发表的论文中,我们发现了严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染与中风病理相似但复杂的病理生理学。患有其他全身性合并症(如糖尿病、高血压或任何呼吸系统疾病)的患者,在感染SARS-CoV-19时,在重症监护管理中会形成致命组合。此外,由于COVID-19和中风存在共同的风险因素,对于医疗管理来说,它们是一种致命的组合。在本综述中,我们讨论了与中风相关的COVID-19治疗方法中的共同病理生理学、辅助风险因素、挑战及进展。