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姜黄素作为乳牙根管充填材料的临床和影像学评价:一项随机对照试验

Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial.

作者信息

Bommareddy Charishma Sai, Ramkumar Hemalatha, Dakshinamurthy Senthil, Paulindraraj Shankar, Jayakaran Trophimus Gnanabagyan, Shankar Karthika

机构信息

Department of Pediatric and Preventive Dentistry, SRM Dental College, Chennai, Tamil Nadu, India.

出版信息

Int J Clin Pediatr Dent. 2022;15(Suppl 1):S35-S39. doi: 10.5005/jp-journals-10005-2128.

DOI:10.5005/jp-journals-10005-2128
PMID:35645494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9108815/
Abstract

AIM AND OBJECTIVE

To evaluate the clinical and radiographic success rates of curcumin, curcumin and calcium hydroxide in equal proportions and calcium hydroxide as an obturation material compared to curcumin and calcium hydroxidet (Metapex).

MATERIALS AND METHODS

This study included 64 primary molars with irreversible pulpitis indicated for single visit pulpectomy. After obtaining informed consent from the parents, all the teeth were randomly allocated to one of four groups. Pulpectomy was performed using rubber dam isolation and was obturated. The samples were categorized into the four groups based on obturation material namely, group A: curcumin with calcium hydroxide in equal proportions, group B: curcumin, group C: calcium hydroxide, and group D: Metapex. Clinical and radiographic outcomes were evaluated at time intervals of 10 days, 1 month, 3 months, and 6 months. Data was subjected to statistical analysis. Chi-square tests were used compare the groups.

RESULTS

At the end of 6 months, clinical and radiographic success rates of groups A, B, and C showed 81.3%, 61.5%, and 93.8%, respectively, while group D had 100% success rate.

CONCLUSION

Among the four groups, the hierarchy of success rates are as follows: Metapex > calcium hydroxide > curcumin and calcium hydroxide > curcumin. However, various formulations and combinations of curcumin can still be extended with larger sample size.

CLINICAL SIGNIFICANCE

Curcumin and calcium hydroxide paste can be used as an obturating material with further follow-up studies.

HOW TO CITE THIS ARTICLE

Bommareddy CS, Ramkumar H, Dakshinamurthy S, Clinical and Radiographic Evaluation of Curcumin as an Obturation Material in Deciduous Teeth: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2022;15(S-1):S35-S39.

摘要

目的

评估姜黄素、等比例姜黄素与氢氧化钙以及氢氧化钙作为根管充填材料与姜黄素和氢氧化钙(Metapex)相比的临床和影像学成功率。

材料与方法

本研究纳入64颗因不可逆性牙髓炎需一次性根管治疗的乳磨牙。在获得家长知情同意后,将所有牙齿随机分为四组。使用橡皮障隔离进行根管治疗并充填。根据充填材料将样本分为四组,即A组:等比例姜黄素与氢氧化钙;B组:姜黄素;C组:氢氧化钙;D组:Metapex。在10天、1个月、3个月和6个月的时间间隔评估临床和影像学结果。对数据进行统计分析。采用卡方检验比较各组。

结果

在6个月末,A组、B组和C组的临床和影像学成功率分别为81.3%、61.5%和93.8%,而D组成功率为100%。

结论

在四组中,成功率排序如下:Metapex>氢氧化钙>姜黄素与氢氧化钙>姜黄素。然而,姜黄素的各种配方和组合仍可通过更大样本量进行扩展研究。

临床意义

姜黄素和氢氧化钙糊剂可作为根管充填材料用于进一步的随访研究。

如何引用本文

Bommareddy CS, Ramkumar H, Dakshinamurthy S, 乳牙根管充填材料姜黄素的临床和影像学评价:一项随机对照试验。《国际临床儿科牙科学杂志》2022;15(S - 补编1):S35 - S39。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3edb/9108815/75c6f9930e5f/ijcpd-15-s35-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3edb/9108815/932270a2fa72/ijcpd-15-s35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3edb/9108815/712eecc3f116/ijcpd-15-s35-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3edb/9108815/75c6f9930e5f/ijcpd-15-s35-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3edb/9108815/932270a2fa72/ijcpd-15-s35-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3edb/9108815/712eecc3f116/ijcpd-15-s35-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3edb/9108815/75c6f9930e5f/ijcpd-15-s35-g003.jpg

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