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1型糖尿病患者唾液成分和牙菌斑与龋齿状况的关系评估

Evaluation of Salivary Components and Dental Plaque in Relation to Dental Caries Status in Type 1 Diabetes Mellitus.

作者信息

Manjushree R, Anandakrishna Latha, Prasad Ks Keerthi, Shetty Ashmitha K

机构信息

Department of Pedododntics and Preventive Dentistry, Bangalore Institute of Dental Sciences, Bengaluru, Karnataka, India.

Department of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, MS Ramaiah University of Applied Sciences, Bengaluru, Karnataka, India.

出版信息

Int J Clin Pediatr Dent. 2022;15(Suppl 2):S121-S125. doi: 10.5005/jp-journals-10005-2325.

Abstract

PURPOSE

To evaluate the dental caries prevalence in Type 1 Diabetes Mellitus (T1DM) as compared to healthy children and, to assess the salivary components (flow rate, glucose, α-Amylase, ) and dental plaque in relation to their dental caries status.

METHODS

Dental caries were estimated by using the DMFS index and dental plaque by Sillness and Loe plaque index. The following methods were used to assess the salivary components; draining method to determine the flow rate; glucose oxidase peroxidase method for glucose; substrate method for α-Amylase, Mitis Salivarius Bacitracin agar was used to culture .

RESULTS

Caries prevalence was significantly lower in T1DM. In the diabetic group, a significant positive correlation was found between DMFS value and plaque, DMFS value and salivary glucose, and also with DMFS value and salivary α-Amylase. A significant negative correlation was found between the DMFS value and the unstimulated salivary flow rate. The multivariate regression analysis demonstrated that decrease in the unstimulated salivary flow rate to be significantly associated with increasing DMFS values.

CONCLUSION

The caries prevalence was found to be low in T1DM when compared to the healthy children, the cause for it being related to the low plaque scores. Low caries prevalence could also be due to the restriction of sucrose in their diet.

CLINICAL SIGNIFICANCE

As clinicians, along with restoring the smiles of a child patient, we have to retrospectively analyze the factors involved in the causation of dental caries. Educating the parents and the child in regard to this will help prevent the occurrence of any new carious lesion.

HOW TO CITE THIS ARTICLE

Manjushree R, Anandakrishna L, Prasad KS K, . Evaluation of Salivary Components and Dental Plaque in Relation to Dental Caries Status in Type 1 Diabetes Mellitus. Int J Clin Pediatr Dent 2022;15(S-2):S121-S125.

摘要

目的

评估1型糖尿病(T1DM)患儿与健康儿童相比的龋齿患病率,并评估唾液成分(流速、葡萄糖、α淀粉酶等)和牙菌斑与他们龋齿状况的关系。

方法

采用DMFS指数评估龋齿情况,用Silness和Loe菌斑指数评估牙菌斑。采用以下方法评估唾液成分;引流法测定流速;葡萄糖氧化酶过氧化物酶法测定葡萄糖;α淀粉酶采用底物法测定,使用变形链球菌琼脂培养基培养。

结果

T1DM患儿的龋齿患病率显著较低。在糖尿病组中,DMFS值与菌斑、DMFS值与唾液葡萄糖以及DMFS值与唾液α淀粉酶之间均存在显著正相关。DMFS值与非刺激性唾液流速之间存在显著负相关。多元回归分析表明,非刺激性唾液流速降低与DMFS值增加显著相关。

结论

与健康儿童相比,T1DM患儿的龋齿患病率较低,原因与菌斑得分低有关。龋齿患病率低也可能是由于他们饮食中蔗糖受限。

临床意义

作为临床医生,除了恢复儿童患者的笑容外,我们还必须回顾性分析龋齿病因相关因素。就此对家长和孩子进行教育将有助于预防任何新的龋损发生。

如何引用本文

Manjushree R, Anandakrishna L, Prasad KS K, 等。1型糖尿病患者唾液成分和牙菌斑与龋齿状况的关系评估。《国际临床儿科牙科学杂志》2022;15(S-2):S121-S125。

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