Raeymaeckers Steven P M J, De Brucker Yannick, Tosi Maurizio, Buls Nico, De Mey Johan
Department of Radiology, UZ Brussel, Brussels 1090, Belgium.
Department of Anesthesiology, UZ Brussel, Brussels 1090, Belgium.
Int J Biomed Imaging. 2022 May 20;2022:2984789. doi: 10.1155/2022/2984789. eCollection 2022.
A multiphase 4DCT technique can be useful for the detection of parathyroid adenomas. Up to 16 different phases can be obtained without significant increase of exposure dose using wide beam axial scanning. This technique also allows for the calculation of perfusion parameters in suspected lesions. We present data on 19 patients with histologically proven parathyroid adenomas. We find a strong correlation between 2 perfusion parameters when comparing parathyroid adenomas and thyroid tissue: parathyroid adenomas show a 55% increase in blood flow (BF) ( < 0.001) and a 50% increase in blood volume (BV) ( < 0.001) as compared to normal thyroid tissue. The analysis of the ROC curve for the different perfusion parameters demonstrates a significantly high area under the curve for BF and BV, confirming these two perfusion parameters to be a possible discriminating tool to discern between parathyroid adenomas and thyroid tissue. These findings can help to discern parathyroid from thyroid tissue and may aid in the detection of parathyroid adenomas.
多期4DCT技术有助于甲状旁腺腺瘤的检测。使用宽束轴向扫描，在不显著增加辐射剂量的情况下可获得多达16个不同时相。该技术还能计算可疑病变的灌注参数。我们展示了19例经组织学证实的甲状旁腺腺瘤患者的数据。在比较甲状旁腺腺瘤和甲状腺组织时，我们发现两个灌注参数之间存在很强的相关性：与正常甲状腺组织相比，甲状旁腺腺瘤的血流量（BF）增加55%（<0.001），血容量（BV）增加50%（<0.001）。对不同灌注参数的ROC曲线分析显示，BF和BV的曲线下面积显著较高，证实这两个灌注参数可能是区分甲状旁腺腺瘤和甲状腺组织的鉴别工具。这些发现有助于区分甲状旁腺和甲状腺组织，可能有助于甲状旁腺腺瘤的检测。
