Wang Liren, Jiang Jia, Lin Hai, Zhu Tonghe, Cai Jiangyu, Su Wei, Chen Jiebo, Xu Junjie, Li Yamin, Wang Jing, Zhang Kai, Zhao Jinzhong
Department of Sports Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Regenerative Sports Medicine and Translational Youth Science and Technology Innovation Workroom, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Front Bioeng Biotechnol. 2022 May 13;10:908751. doi: 10.3389/fbioe.2022.908751. eCollection 2022.
Regenerative sports medicine aims to address sports and aging-related conditions in the locomotor system using techniques that induce tissue regeneration. It also involves the treatment of meniscus and ligament injuries in the knee, Achilles' tendon ruptures, rotator cuff tears, and cartilage and bone defects in various joints, as well as the regeneration of tendon-bone and cartilage-bone interfaces. There has been considerable progress in this field in recent years, resulting in promising steps toward the development of improved treatments as well as the identification of conundrums that require further targeted research. In this review the regeneration techniques currently considered optimal for each area of regenerative sports medicine have been reviewed and the time required for feasible clinical translation has been assessed. This review also provides insights into the direction of future efforts to minimize the gap between basic research and clinical applications.
再生运动医学旨在利用诱导组织再生的技术来解决运动系统中与运动和衰老相关的病症。它还涉及膝关节半月板和韧带损伤、跟腱断裂、肩袖撕裂以及各种关节的软骨和骨缺损的治疗，以及肌腱-骨和软骨-骨界面的再生。近年来该领域取得了相当大的进展，朝着开发改进治疗方法以及识别需要进一步针对性研究的难题迈出了有前景的步伐。在这篇综述中，对目前被认为是再生运动医学各个领域最佳的再生技术进行了综述，并评估了可行的临床转化所需的时间。这篇综述还为未来努力的方向提供了见解，以尽量缩小基础研究与临床应用之间的差距。
