bacteremia in a human immunodeficiency virus-negative patient with liver cirrhosis: A case report.

BACKGROUND

With the increasing prevalence of human immunodeficiency virus (HIV), the incidence of () bacteremia has also increased. As a common affliction of acquired immunodeficiency syndrome patients, infection is associated in these patients with severe sepsis and high mortality. In contrast, bacteremia is rarely seen in HIV-negative patients, and has never been reported from the blood of patients with liver cirrhosis.

CASE SUMMARY

We evaluated a 55-year-old Chinese male patient who had been admitted to the hospital with abdominal distension of unknown cause of one-week duration, accompanied by diarrhea, shortness of breath, and occasional fever. Based on these indicators of abnormal inflammation and fever, we suspected the presence of an infection. Although evidence of microbial infection was not found in routine clinical tests and the patient did not show typical clinical symptoms of infection with , next-generation sequencing of blood samples nevertheless demonstrated the presence of , which was subsequently isolated from blood samples grown in conventional BacT/ALERT FA blood culture bottles.

CONCLUSION

Our findings demonstrate that HIV-negative liver cirrhosis patients can also be infected with .