Department of Urology, Yuechi People's Hospital, Guang'an, Sichuan, China.
Eur Rev Med Pharmacol Sci. 2022 May;26(10):3430-3436. doi: 10.26355/eurrev_202205_28836.
The aim of the study was to investigate the efficacy of stone baskets combined with flexible ureteroscope holmium laser lithotripsy (FURL) in the treatment of lower calyceal stones (LCS).
A total of 216 patients with LCS who underwent FURL in our hospital were analyzed retrospectively and divided into observation group (n=129, with stone basket) and control group (n=87, without the stone basket), according to whether the stone basket was used during FURL. The operation time, stone size, stone clearance rate, steinstrasse incidence rate and complication rate were collected and analyzed.
There were no significant differences between the two groups in preoperative gender, BMI, age, stone size and comorbid diseases (p > 0.05); no significant differences between the two groups in the change of procalcitonin, C-reactive protein, white blood cell count and hemoglobin after the operation (p>0.05); the operation time in the observation group was significantly higher than that in the control group (80.12±8.25 vs. 61.93±6.55, p=0.019); the short-term stone clearance rate (85.27% vs. 66.67%, p 0.001) and long-term stone clearance rate (95.35% vs. 85.06%, p=0.021) of the observation group were significantly higher than those of the control group; the incidence rate of steinstrasse (0% vs. 8.05%, p<0.001) and overall complications (7.75% vs. 16.09%, p=0.009) in the observation group were significantly lower than those in the control group.
Stone basket combined with FURL is safe and feasible for the treatment of LCS, which can improve the stone clearance rate and reduce the risk of steinstrasse formation after the operation.
研究目的在于探讨在处理下盏结石(LCS)时,使用取石篮联合输尿管软镜钬激光碎石术(FURL)的疗效。
回顾性分析 216 例在我院接受 FURL 的 LCS 患者,根据术中是否使用取石篮将其分为观察组(n=129,使用取石篮)和对照组(n=87,未使用取石篮)。收集并分析两组患者的手术时间、结石大小、结石清除率、石街发生率和并发症发生率。
两组患者术前性别、BMI、年龄、结石大小和合并症比较,差异无统计学意义(p>0.05);两组患者术后降钙素原、C 反应蛋白、白细胞计数和血红蛋白变化比较,差异无统计学意义(p>0.05);观察组手术时间显著长于对照组(80.12±8.25 vs. 61.93±6.55,p=0.019);观察组短期结石清除率(85.27% vs. 66.67%,p<0.001)和长期结石清除率(95.35% vs. 85.06%,p=0.021)显著高于对照组;观察组石街发生率(0% vs. 8.05%,p<0.001)和总并发症发生率(7.75% vs. 16.09%,p=0.009)显著低于对照组。
取石篮联合 FURL 治疗 LCS 安全可行,可提高结石清除率,降低术后石街形成风险。