Amsterdam UMC location University of Amsterdam, Department of Internal Medicine, Division of Geriatrics, Meibergdreef, Amsterdam, The Netherlands.
Amsterdam Public Health, Aging & Later Life, Amsterdam, The Netherlands.
J Gerontol A Biol Sci Med Sci. 2022 Nov 21;77(11):2298-2305. doi: 10.1093/gerona/glac113.
We investigated prospectively among community-dwelling older adults aged 65 years and older whether a larger kyphosis angle is associated with poorer physical performance (balance, muscle strength, or both), and whether this association is unidirectional.
Male and female participants performed a multicomponent physical performance test with subscores for gait, muscle strength, and balance at baseline and after 2 years. Hand grip strength was also measured at baseline and at follow-up. The Cobb angle was measured on DXA-based Vertebral Fracture Assessments, made at the baseline and follow-up visit. Through linear and logistic regression analysis, we investigated the association between the kyphosis angle and physical performance and vice versa. We stratified for sex, and tested for effect modification by age and study center.
The mean kyphosis angle was 37° and 15% of the participants (n = 1 220, mean age 72.9 ± 5.7 years) had hyperkyphosis (Cobb angle ≥50°). A larger kyphosis angle at baseline was independently associated with a poorer total physical performance score in women of the oldest quartile (≥77 years) in both the cross-sectional and longitudinal analyses (baseline B -0.32, 95% confidence interval [CI] -0.56-0.08; follow-up B 0.32, 95% CI -0.55-0.10). There was no association between physical performance at baseline and kyphosis progression.
A larger kyphosis angle is independently associated with a poorer physical performance at baseline and over time, and the direction of this association is unidirectional. These results emphasize the importance of early detection and treatment of hyperkyphosis to prevent further worsening of the kyphosis angle, thereby potentially preserving physical performance.
我们前瞻性地研究了社区居住的 65 岁及以上老年人,较大的后凸角度是否与较差的身体表现(平衡、肌肉力量或两者兼而有之)相关,以及这种关联是否具有单向性。
男性和女性参与者在基线和 2 年后进行了多组分身体表现测试,其中包括步态、肌肉力量和平衡的子分数。基线和随访时还测量了手握力。Cobb 角是在基于 DXA 的脊柱骨折评估上测量的,在基线和随访时进行。通过线性和逻辑回归分析,我们调查了后凸角度与身体表现之间的关联,以及反之亦然。我们按性别分层,并测试了年龄和研究中心的效应修饰作用。
平均后凸角度为 37°,15%的参与者(n=1220,平均年龄 72.9±5.7 岁)存在后凸过度(Cobb 角≥50°)。在横断面和纵向分析中,基线时较大的后凸角度与年龄最大四分位数(≥77 岁)的女性总身体表现评分较差独立相关(基线 B-0.32,95%置信区间 [CI]-0.56-0.08;随访 B0.32,95%CI-0.55-0.10)。身体表现的基线与后凸进展之间没有关联。
较大的后凸角度与基线和随时间推移的身体表现较差独立相关,并且这种关联的方向是单向的。这些结果强调了早期检测和治疗后凸过度以防止后凸角度进一步恶化,从而有可能保持身体表现的重要性。