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健康人和闭塞性动脉疾病患者运动时经皮氧分压的反应

Transcutaneous oxygen tension response to exercise in health and in occlusive arterial disease.

作者信息

Christensen K S, Larsen J F, Klaerke M

出版信息

Acta Chir Scand. 1986 Nov;152:657-60.

PMID:3564818
Abstract

Transcutaneous oxygen tension (TcPO2) was measured on the foot at rest and during exercise in supine position in 21 clinically healthy controls and in 17 patients with intermittent claudication. All patients had ankle pressure greater than 50 mmHg and arteriographically proven peripheral vascular disease. Resting TcPO2 was significantly lower in the patient group than in the control group, though with considerable overlap between the groups. During exercise, however, TcPO2 showed highly significant decrease in the patient group. The median change following exercise in that group was -90% (range -54 to -100%) of the resting value. In the control group there was no significant fall in TcPO2 during 4 min exercise--median change -8% (range +30 to -34%). During exercise there was no overlap between the patient and the control group. Foot TcPO2 measurement during exercise in supine position is a simple, noninvasive and highly specific test for identifying patients with significant peripheral vascular disease.

摘要

对21名临床健康对照者和17名间歇性跛行患者在静息状态及仰卧位运动时的足部经皮氧分压(TcPO2)进行了测量。所有患者的踝部压力均大于50 mmHg,且经动脉造影证实患有周围血管疾病。患者组的静息TcPO2显著低于对照组,尽管两组之间存在相当大的重叠。然而,在运动期间,患者组的TcPO2出现了极显著下降。该组运动后的中位数变化为静息值的-90%(范围为-54%至-100%)。在对照组中,4分钟运动期间TcPO2没有显著下降——中位数变化为-8%(范围为+30%至-34%)。运动期间患者组和对照组之间没有重叠。仰卧位运动时测量足部TcPO2是一种用于识别患有严重周围血管疾病患者的简单、非侵入性且高度特异的检查方法。

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引用本文的文献

1
Discordance of peripheral artery disease diagnosis using exercise transcutaneous oxygen pressure measurement and post-exercise ankle-brachial index.运动经皮氧分压测量与运动后踝臂指数诊断外周动脉疾病的不相符。
Sci Rep. 2020 May 4;10(1):7419. doi: 10.1038/s41598-020-64276-x.