de Groote P, Millaire A, Deklunder G, Marache P, Decoulx E, Ducloux G
Department of Cardiology C, Cardiology Hospital, University of Lille, France.
Angiology. 1995 Feb;46(2):115-22. doi: 10.1177/000331979504600204.
Few studies have compared sensitivities of ankle-to-brachial index (ABI) and transcutaneous oxygen tension (TcPO2) in a large group of patients with Leriche stage II intermittent claudication.
111 patients (138 limbs) with a stable chronic (> three months) intermittent claudication and significant peripheral vascular disease (PVD) proved by angiography were studied. They performed a treadmill test (10%, 3 km/hr) limited by limb pain. ABI and TcPO2 were measured before, just after exercise, and after three and ten minutes of recovery in supine position. Sensitivities per patient for ABI and TcPO2 were respectively at rest: 82.9% and 28.8%, and after exercise: 88.3% and 62.2%. Sensitivities per leg (n = 138) for ABI and TcPO2 were respectively at rest: 73.9% and 26.8%, and after exercise: 82.6% and 34%. The sensitivity of TcPO2 increased to 56.5% after three minutes of recovery but was always less than that of ABI, which was maximal just after exercise (82.6%). The sensitivity of the regional perfusion index was similar to that of TcPO2. The sensitivity of TcPO2 increased with respect to the Leriche stage and the number of lesions but was always lower than that of ABI. There was a weak correlation between TcPO2 and ABI after exercise, but no correlation was noted between maximal walking distance, ABI, and TcPO2.
TcPO2 is not required in patients with Leriche stage II intermittent claudication but might be useful either in severely affected patients (Leriche stage III or IV) or in selected patients.
很少有研究在一大群勒里什II期间歇性跛行患者中比较踝臂指数（ABI）和经皮氧分压（TcPO2）的敏感性。
对111例（138条肢体）患有稳定的慢性（>3个月）间歇性跛行且经血管造影证实有明显外周血管疾病（PVD）的患者进行了研究。他们进行了受肢体疼痛限制的平板运动试验（10%，3公里/小时）。在运动前、运动刚结束后以及仰卧位恢复3分钟和10分钟后测量ABI和TcPO2。每位患者在静息时ABI和TcPO2的敏感性分别为：82.9%和28.8%，运动后分别为：88.3%和62.2%。每条腿（n = 138）在静息时ABI和TcPO2的敏感性分别为：73.9%和26.8%，运动后分别为：82.6%和34%。恢复3分钟后TcPO2的敏感性增至56.5%，但始终低于ABI，ABI在运动刚结束时敏感性最高（82.6%）。区域灌注指数的敏感性与TcPO2相似。TcPO2的敏感性随勒里什分期和病变数量增加，但始终低于ABI。运动后TcPO2与ABI之间存在弱相关性，但最大步行距离、ABI和TcPO2之间未发现相关性。
勒里什II期间歇性跛行患者不需要检测TcPO2，但在病情严重的患者（勒里什III期或IV期）或特定患者中可能有用。
