Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto da Criança e do Adolescente, Departamento de Pediatria, Unidade de Infectologia Pediátrica, São Paulo, São Paulo, Brazil.
Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto da Criança e do Adolescente, Departamento de Pediatria, Unidade de Emergência Pediátrica, São Paulo, São Paulo, Brazil.
Rev Inst Med Trop Sao Paulo. 2022 May 25;64:e34. doi: 10.1590/S1678-9946202264034. eCollection 2022.
This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP.
本研究旨在评估儿童患者中的 COVID-19 和其他呼吸道病毒。在 2020 年 4 月 17 日至 9 月 30 日期间，我们收集了 1044 名年龄小于 18 岁的有症状患者的 1566 份呼吸道样本，以评估 SARS-CoV-2 感染情况。其中，919 份样本用于分析其他呼吸道病原体（ORP）。纳入实验室确诊的 COVID-19 或 ORP 患者。我们评估了 76 例儿科 COVID-19 感染和 157 例其他呼吸道病毒感染。157 例中 132 例（84%）为鼻病毒感染。COVID-19 患者的年龄明显大于 ORP 患者，且发热、头痛和肺炎的发生率也高于 ORP 患者。与 ORP 患者相比，SARS-CoV-2 患者的白细胞计数中位数明显更低（6470 对 8170；p=0.02）。COVID-19 患者的症状明显比 ORP 患者更严重。
