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冷热水水疗(根据塞巴斯蒂安·克奈普)对免疫刺激的影响:一项非随机、对照、探索性、混合方法临床研究。

The Effect of Cold-Water Hydrotherapy According to Sebastian Kneipp for Immune Stimulation: A Nonrandomized, Controlled, Explorative, Mixed-Methods Clinical Study.

机构信息

Department of Pediatric Oncology/Hematology, Otto-Heubner Centre for Pediatric and Adolescent Medicine (OHC), Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin Institute of Health, Berlin, Germany.

Department of Human Medicine and Integrated Accompanying Studies in Anthroposophic Medicine (IBAM), University of Witten/Herdecke Faculty of Health, Herdecke, Germany.

出版信息

J Integr Complement Med. 2022 Sep;28(9):749-756. doi: 10.1089/jicm.2022.0476. Epub 2022 Jun 1.

Abstract

Home-based hydrotherapy leads to fewer missed kindergarten-days in total. In the application group, more fever days could be registered. Hydrotherapy, according to the hormesis principle by Sebastian Kneipp, aims to reduce infections of the lower respiratory tract. Parents participation motivated by increase in applicable health knowledge for their children. This study investigates the effect of cold-water hydrotherapy stimulation according to the hormesis principle by Sebastian Kneipp on the number of missing kindergarten-days, fever days, and respiratory tract infections in children aged 3-6 years. A nonrandomized, controlled, explorative, mixed-methods clinical study. The hydrotherapeutic intervention treated children aged 3-6 years with Kneipp arm affusions over 6 weeks. The control group received no intervention. Number of missed kindergarten-days, fever days, and respiratory tract infections were assessed by means of a digital diary. Through a self-developed structured questionnaire, sociodemographic data of both groups were compared and reason for participation in the study was recorded and qualitatively evaluated. Twenty children participants and their parents in the intervention group and 18 in the control group were evaluated. The intervention was conducted at home by the parents. Statistical analysis revealed no significant differences between the groups but still showed intermediate effect sizes (indicating an underpowered study). These effect sizes point to a potentially lower proportion of children in the application group versus the control group with missed kindergarten-days in total ( = 0.67), days missed due to fever ( = 0.29), and infections of the lower respiratory tract ( = 0.60). In a future study, these parameters will thus serve as promising factors for evaluation. Parent's stated reasons for participation interest were to improve health, increase their own health knowledge, and because of their interest in alternative therapies and to support research. Cold-water hydrotherapy stimulation, according to the hormesis principle by Sebastian Kneipp, did reduce the number of days absent in kindergarten in total in the intervention group and lower respiratory tract infections occurred less frequently. Parent' participation interest demonstrated a desire to increase health literacy and implement this with their own children. Due to the small sample size, the results should be interpreted cautiously. German Register of Clinical Trials (DRKS): ID 00017562.

摘要

家庭水疗可导致总缺课日减少。在应用组中,更多的发热天数可以被记录。水疗根据 Sebastian Kneipp 的应激原理,旨在减少下呼吸道感染。父母参与的动机是为孩子增加适用的健康知识。

本研究调查了根据 Sebastian Kneipp 的应激原理的冷水水疗刺激对 3-6 岁儿童缺课日、发热日和呼吸道感染的影响。

一项非随机、对照、探索性、混合方法的临床研究。水疗干预治疗了 3-6 岁的儿童,在 6 周内进行 Kneipp 手臂灌注。对照组未接受干预。通过数字日记评估缺课日、发热日和呼吸道感染的数量。通过自行开发的结构化问卷,比较了两组的社会人口统计学数据,并记录和定性评估了参与研究的原因。

干预组有 20 名儿童及其父母,对照组有 18 名儿童及其父母。干预由父母在家进行。统计分析显示两组之间没有显著差异,但仍显示出中等的效应大小(表明研究效力不足)。这些效应大小表明,应用组与对照组相比,总缺课日( = 0.67)、因发热缺课日( = 0.29)和下呼吸道感染的儿童比例可能较低( = 0.60)。在未来的研究中,这些参数将作为有前途的评估因素。家长参与的原因是为了改善健康,增加自己的健康知识,以及对替代疗法的兴趣,并支持研究。

根据 Sebastian Kneipp 的应激原理的冷水水疗刺激确实减少了干预组总缺课日的数量,并且下呼吸道感染的发生频率较低。父母的参与兴趣表明他们希望提高健康素养,并将其应用于自己的孩子。由于样本量小,结果应谨慎解释。

德国临床试验注册处(DRKS):ID 00017562。

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