Institute of Social Medicine, Epidemiology and Health Economics, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Berlin, Germany
Department of Pediatrics, Division of Oncology and Hematology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Berlin, Germany.
BMJ Open. 2023 Jul 9;13(7):e070951. doi: 10.1136/bmjopen-2022-070951.
Hydrotherapy is a traditional prevention and treatment strategy. This study's aim is to systematically review all available randomised controlled trials (RCTs) investigating clinical effects of hydrotherapy according to Kneipp which is characterised by cold water applications.
RCTs on disease therapy and prevention with Kneipp hydrotherapy were included. Study participants were patients and healthy volunteers of all age groups. MEDLINE (via PubMed), Scopus, Central, CAMbase, and opengrey.eu were systematically searched through April 2021 without language restrictions and updated by searching PubMed until April 6th 2023. Risk of bias was assessed using the Cochrane tool version 1.ResultsTwenty RCTs (N=4247) were included. Due to high heterogeneity of the RCTs, no meta-analysis was performed. Risk of bias was rated as unclear in most of the domains. Of 132 comparisons, 46 showed significant positive effects in favour of hydrotherapy on chronic venous insufficiency, menopausal symptoms, fever, cognition, emotional function and sickness absenteeism. However, 81 comparisons showed no differences between groups and 5 were in favour of the respective control group. Only half of the studies reported safety issues.
Although RCTs on Kneipp hydrotherapy seem to show positive effects in some conditions and outcomes, it remains difficult to ascertain treatment effects due to the high risk of bias and heterogeneity of most of the considered studies. Further high-quality RCTs on Kneipp hydrotherapy are urgently warranted.
CRD42021237611.
水疗是一种传统的预防和治疗策略。本研究旨在系统地综述所有可用的随机对照试验(RCT),以评估根据 Kneipp 原则进行的冷水应用的水疗对临床的影响。
纳入了关于疾病治疗和预防的 Kneipp 水疗的 RCT。研究对象为所有年龄段的患者和健康志愿者。系统地检索了 MEDLINE(通过 PubMed)、Scopus、CENTRAL、CAMbase 和 opengrey.eu,检索时间截至 2021 年 4 月,无语言限制,并通过 2023 年 4 月 6 日检索 PubMed 进行了更新。使用 Cochrane 工具版本 1 评估偏倚风险。
共纳入 20 项 RCT(N=4247)。由于 RCT 的异质性很高,因此未进行荟萃分析。大多数领域的偏倚风险被评为不清楚。在 132 项比较中,有 46 项显示水疗对慢性静脉功能不全、更年期症状、发热、认知、情绪功能和病假缺勤有显著的积极影响。然而,81 项比较显示组间无差异,5 项比较支持相应的对照组。只有一半的研究报告了安全性问题。
尽管 Kneipp 水疗的 RCT 似乎在某些情况下和结局中显示出积极的效果,但由于大多数研究的偏倚风险和异质性较高,仍然难以确定治疗效果。迫切需要进一步开展高质量的 Kneipp 水疗 RCT。
PROSPERO 注册号:CRD42021237611。