Y.H. Kwan, MD, PhD, Programme in Health Services & Systems Research, Duke NUS Medical School, Singapore, Department of Rheumatology and Immunology, Singapore General Hospital, and Department of Pharmacy, Faculty of Science, National University of Singapore;
W. Fong, MBBS, MRCP(UK), FAMS, Department of Rheumatology and Immunology, Singapore General Hospital, Duke NUS Medical School, and Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore.
J Rheumatol. 2022 Sep;49(9):1006-1011. doi: 10.3899/jrheum.210980. Epub 2022 Jun 1.
Health-related quality of life (HRQOL) is an important aspect in the management of chronic diseases such as spondyloarthritis (SpA). A promising approach to reduce respondent burden when measuring HRQOL is the use of shorter patient-reported outcome measures (PROMs) delivered using computerized adaptive tests (CATs). However, the lack of an item bank that covers the entire continuum of the HRQOL domain impedes the development of CATs to measure HRQOL among patients with SpA. We aimed to develop an item bank for an HRQOL measure among patients with SpA based on the items from existing validated PROMs.
This study is guided by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) and Patient Reported Outcomes Measurement Information System (PROMIS) standards. Relevant articles were retrieved from PubMed, Embase, and PsycINFO (Ovid) databases. Items from existing PROMs were binned and winnowed according to the facets of HRQOL in the World Health Organization (WHO) quality of life framework.
We identified 147 relevant articles, from which written permission was obtained for including 31 PROMs into the item bank. PROMs contained 1039 items, which underwent binning and winnowing. This resulted in 968 items covering 23 domains of HRQOL in the WHO framework, with the number of items within each domain ranging from 1 to 453.
We created an item bank to measure HRQOL among patients with SpA using items from validated PROMs. This set can provide the foundation for the development of CATs to measure HRQOL among patients with SpA.
健康相关生活质量（HRQOL）是管理诸如脊柱关节炎（SpA）等慢性病的一个重要方面。在测量 HRQOL 时，减少应答者负担的一种有前途的方法是使用计算机化自适应测试（CAT）来提供更简短的患者报告的结果测量（PROM）。然而，缺乏涵盖 HRQOL 领域整个连续体的项目库，阻碍了用于测量 SpA 患者 HRQOL 的 CAT 的开发。我们旨在基于现有的验证过的 PROM 中的项目，为 SpA 患者的 HRQOL 测量开发一个项目库。
本研究遵循系统评价和荟萃分析的首选报告项目（PRISMA）和患者报告的结果测量信息系统（PROMIS）标准。从 PubMed、Embase 和 PsycINFO（Ovid）数据库中检索相关文章。根据世界卫生组织（WHO）生活质量框架中的 HRQOL 方面，将现有 PROM 中的项目进行分类和筛选。
我们确定了 147 篇相关文章，其中 31 篇 PROM 获得了包含在项目库中的书面许可。PROM 包含 1039 个项目，这些项目经过分类和筛选。这导致了 968 个涵盖 WHO 框架 23 个 HRQOL 领域的项目，每个领域的项目数量从 1 到 453 不等。
我们使用经过验证的 PROM 中的项目为 SpA 患者创建了一个测量 HRQOL 的项目库。这个集合可以为开发用于测量 SpA 患者 HRQOL 的 CAT 提供基础。
