Department of Rheumatology & Immunology, Singapore General Hospital, Singapore, Singapore.
Medicine Academic Clinical Programme, Singapore General Hospital, Singapore, Singapore.
Health Qual Life Outcomes. 2020 Jan 2;18(1):2. doi: 10.1186/s12955-019-1255-1.
To develop separate item banks for three health domains of health-related quality of life (HRQOL) ranked as important by Singaporeans - physical functioning, social relationships, and positive mindset.
We adapted the Patient Reported Outcomes Measurement Information System Qualitative Item Review protocol, with input and endorsement from laymen and experts from various relevant fields. Items were generated from 3 sources: 1) thematic analysis of focus groups and in-depth interviews for framework (n = 134 participants) and item(n = 52 participants) development, 2) instruments identified from a literature search (PubMed) of studies that developed or validated a HRQOL instrument among adults in Singapore, 3) a priori identified instruments of particular relevance. Items from these three sources were "binned" and "winnowed" by two independent reviewers, blinded to the source of the items, who harmonized their selections to generate a list of candidate items (each item representing a subdomain). Panels with lay and expert representation, convened separately for each domain, reviewed the face and content validity of these candidate items and provided inputs for item revision. The revised items were further refined in cognitive interviews.
Items from our qualitative studies (51 physical functioning, 44 social relationships, and 38 positive mindset), the literature review (36 instruments from 161 citations), and three a priori identified instruments, underwent binning, winnowing, expert panel review, and cognitive interview. This resulted in 160 candidate items (61 physical functioning, 51 social relationships, and 48 positive mindset).
We developed item banks for three important health domains in Singapore using inputs from potential end-users and the published literature. The next steps are to calibrate the item banks, develop computerized adaptive tests (CATs) using the calibrated items, and evaluate the validity of test scores when these item banks are administered adaptively.
为新加坡人认为重要的三个健康相关生活质量（HRQOL）健康领域 - 身体功能、社会关系和积极心态 - 分别开发单独的项目库。
我们改编了患者报告的结果测量信息系统定性项目审查协议，由来自各个相关领域的外行和专家提供意见和认可。项目来源于 3 个来源：1）对焦点小组和深入访谈的主题分析，用于制定框架（n=134 名参与者）和项目（n=52 名参与者）；2）从文献检索（PubMed）中确定的工具，这些工具在新加坡成年人中开发或验证了 HRQOL 工具；3）事先确定的特别相关的工具。这三个来源的项目进行“分类”和“筛选”，由两位独立评审员进行，评审员对项目来源一无所知，他们协调他们的选择，生成候选项目列表（每个项目代表一个子领域）。分别为每个领域召集具有代表性的外行和专家小组，审查这些候选项目的表面和内容有效性，并提供项目修订意见。经修订的项目在认知访谈中进一步完善。
我们的定性研究（51 项身体功能、44 项社会关系和 38 项积极心态）、文献综述（来自 161 篇引文的 36 项工具）和三个事先确定的工具中的项目经过分类、筛选、专家小组审查和认知访谈。这产生了 160 个候选项目（61 项身体功能、51 项社会关系和 48 项积极心态）。
我们使用潜在最终用户的投入和已发表的文献为新加坡的三个重要健康领域开发了项目库。下一步是校准项目库，使用校准后的项目开发计算机自适应测试（CAT），并在自适应管理这些项目库时评估测试分数的有效性。
