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混合配体复合物处理对小鼠体内¹⁴⁴Ce组织沉积的影响

Modification of 144Ce tissue deposition by mixed ligand complex treatment in mice.

作者信息

Gachályi A, Naményi J, Szegedi I, Varga P L

出版信息

Acta Physiol Hung. 1986;68(3-4):233-40.

PMID:3565034
Abstract

The individual effect of desferrioxamine-B (DFOA), Na3Ca-diethylene-triaminepentaacetic acid (DTPA), DL-penicillamine (PA) and Na-salicylate (SA) has been examined as well as the effect of mixed-ligand treatment on the retention and elimination of 144Ce in mice. It was found that 144Ce could easily be mobilized by a single dose of DTPA. Mixed-ligand (MLCs) treatment did not change the deposition characteristics and translocation kinetics of 144Ce.

摘要

已研究了去铁胺-B(DFOA)、三钠钙二乙烯三胺五乙酸(DTPA)、DL-青霉胺(PA)和水杨酸钠(SA)的个体效应,以及混合配体处理对小鼠体内144Ce保留和消除的影响。发现单剂量的DTPA可轻易促使144Ce迁移。混合配体(MLCs)处理并未改变144Ce的沉积特征和转运动力学。

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