纽约市流感疫苗接种率与 COVID-19 死亡率的生态学研究。
Ecologic study of influenza vaccination uptake and COVID-19 death rate in New York City.
机构信息
Institute for Translational Epidemiology, Icahn School of Medicine at Mount Sinai, New York, USA.
出版信息
BMC Public Health. 2022 Jun 1;22(1):1089. doi: 10.1186/s12889-022-13515-z.
BACKGROUND
The aim of this ecological study was to assess the area-level relationship between cumulative death rate for COVID-19 and historic influenza vaccination uptake in the New York City population.
METHODS
Predictors of COVID-19 death included self-reported influenza vaccination in 2017, as well as four CDC-defined risk factors of severe COVID-19 infection available at the ecological level, which were diabetes, asthma, BMI 30-100 () and hypertension, in addition to race and age (65 + years).
RESULTS
After adjusting for potential confounders, for every one-unit increase in influenza vaccination uptake for each zip code area, the rate of COVID-19 deaths decreased by 5.17 per 100,000 residents (p < 0.0001).
CONCLUSIONS
Zip codes with a higher prevalence of influenza vaccination had lower rates of COVID-19 mortality, inciting the need to further explore the relationship between influenza vaccination uptake and COVID-19 mortality at the individual level.
背景
本生态研究旨在评估纽约市人群中 COVID-19 累计死亡率与既往流感疫苗接种率之间的区域水平关系。
方法
COVID-19 死亡的预测因素包括 2017 年自我报告的流感疫苗接种情况，以及在生态水平上可用的四个与严重 COVID-19 感染相关的 CDC 定义的危险因素，即糖尿病、哮喘、BMI 30-100（）和高血压，此外还有种族和年龄（65+岁）。
结果
在调整了潜在混杂因素后，每个邮政编码区域流感疫苗接种率每增加一个单位，COVID-19 死亡人数减少 5.17 人/10 万人（p<0.0001）。
结论
流感疫苗接种率较高的邮政编码区域 COVID-19 死亡率较低，这促使我们进一步探讨个体层面上流感疫苗接种率与 COVID-19 死亡率之间的关系。
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