Zemishlany Z, Modai I, Apter A, Jerushalmy Z, Samuel E, Tyano S
Acta Psychiatr Scand. 1987 Feb;75(2):127-30. doi: 10.1111/j.1600-0447.1987.tb02763.x.
Platelet serotonin (5-HT) uptake was determined in 15 underweight anorexia nervosa patients and a control group of 15 healthy individuals. The Vmax (picomoles/10(8) platelets/5 min) was 424 +/- 103 in patients and 424 +/- 69 in controls. The Km was 1.19 +/- 0.2 microM in patients and 1.08 +/- 0.17 microM in controls. The differences between the groups were not significant. These findings do not support the hypothesis that serotonin metabolism is disturbed in anorexia nervosa.
测定了15名体重过轻的神经性厌食症患者和15名健康个体组成的对照组的血小板5-羟色胺（5-HT）摄取情况。患者组的最大反应速度（皮摩尔/10⁸个血小板/5分钟）为424±103，对照组为424±69。患者组的米氏常数为1.19±0.2微摩尔，对照组为1.08±0.17微摩尔。两组之间的差异不显著。这些发现不支持神经性厌食症患者血清素代谢紊乱的假说。
