Chowdhury Tutul, Dutta Jui, Noel Pharlin, Islam Ratul, Gonzalez-Peltier Gael, Azad Samzorna, Shankar Malavika, Rayapureddy Aditya Keerthi, Deb Roy Padmaja, Gousy Nicole, Hassan Khondokar N
Internal Medicine, One Brooklyn Health System, Brooklyn, USA.
Medicine, Comilla Medical College, New York City, USA.
Cureus. 2022 Apr 27;14(4):e24520. doi: 10.7759/cureus.24520. eCollection 2022 Apr.
Rheumatoid arthritis is one of the most prevalent musculoskeletal disorders that, when insufficiently treated, results in detrimental sequelae including joint damage and reduced quality of life. Poor patient adherence to medication is a significant blockade to effective management. The purpose of this review is to highlight and discuss the factors responsible for defiance of antirheumatic medication and ways to overcome these barriers. Education level, health literacy, cohabitation status, multi-morbidities, complicated drug regimen, intermittent co-payments, prescribed regimen adverse effects, and cognitive impairment are a few among many common barrier factors leading to poorer outcomes in rheumatoid arthritis. While there is an abundance of inhibitory factors leading to worsening disease progression, they each can be easily dealt with an effective approach at the beginning or during the treatment course to ensure a better outcome.
类风湿性关节炎是最常见的肌肉骨骼疾病之一，若治疗不充分，会导致包括关节损伤和生活质量下降在内的有害后遗症。患者对药物治疗的依从性差是有效管理的重大障碍。本综述的目的是强调和讨论导致抗风湿药物治疗不依从的因素以及克服这些障碍的方法。教育水平、健康素养、同居状况、多种疾病、复杂的药物治疗方案、间歇性共同支付、规定治疗方案的不良反应以及认知障碍是导致类风湿性关节炎预后较差的众多常见障碍因素中的一部分。虽然有大量导致疾病进展恶化的抑制因素，但在治疗开始时或治疗过程中，每一个因素都可以通过有效的方法轻松应对，以确保获得更好的结果。
