Pietropaolo Amelia, Mani Mriganka, Hughes Thomas, Somani Bhaskar K
Department of Urology, University Hospital Southampton NHS Foundation Trust, Southampton SO153FD, UK.
Department of Urology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.
Ther Adv Urol. 2022 May 26;14:17562872221097345. doi: 10.1177/17562872221097345. eCollection 2022 Jan-Dec.
Ureteroscopy and laser stone fragmentation [flexible ureteroscopy and laser lithotripsy (FURSL)] has risen over the last two decades. Laser technology has also evolved over the time, shifting from low- to high-power lasers with the addition of MOSES technology that allows for 'dusting and pop-dusting' of stones. The aim of the study was to look at the outcomes of FURSL in lower pole stones (LPS) using low- and high-power lasers.
In this study, we compared the outcomes of low-power holmium laser (group A, 20 W) and high-power holmium laser (group B, including both 60 W MOSES integrated system and 100 W lasers) for all patients with LPS treated with laser lithotripsy. Data were collected for patient demographics, stone location, size, pre- and postoperative stent, length of stay, complications and stone free rate (SFR).
A total of 284 patients who underwent FURSL procedure for LPS were analysed (168 group A, 116 group B). Outcomes showed that compared with group A, group B had a higher SFR (91.6% 96.5%, = 0.13) and shorter operative time (52 38 min, < 0.001). The median length of stay was <24 h in all groups (day-case procedures). The complication rate was comparable between the two groups but with more infectious complications ( = 7) noted in group A compared with group B ( = 3) ( = 0.53).
Compared with low-power laser, the use of high-power laser for LPS significantly reduced the use of ureteral access sheath (UAS), postoperative stent and procedural time. Although non-statistically significant, the SFR was higher in the high-power group even for relatively larger stone sizes, which was also reflected in a reduction of sepsis-related complication rates with these lasers.
输尿管镜检查和激光碎石术[软性输尿管镜检查和激光碎石术(FURSL)]在过去二十年中得到了广泛应用。随着时间的推移,激光技术也在不断发展,从低功率激光发展到高功率激光,并增加了允许对结石进行“粉末化和弹出式粉末化”的摩西技术。本研究的目的是观察使用低功率和高功率激光治疗下极结石(LPS)的FURSL结果。
在本研究中,我们比较了低功率钬激光(A组,20W)和高功率钬激光(B组,包括60W摩西集成系统和100W激光)对所有接受激光碎石术治疗的LPS患者的治疗效果。收集了患者的人口统计学数据、结石位置、大小、术前和术后支架、住院时间、并发症和结石清除率(SFR)。
共有284例接受FURSL治疗LPS的患者纳入分析(A组168例,B组116例)。结果显示,与A组相比,B组的SFR更高(91.6%对96.5%,P = 0.13),手术时间更短(52对38分钟,P < 0.001)。所有组的中位住院时间均<24小时(日间手术)。两组的并发症发生率相当,但A组(n = 7)的感染性并发症比B组(n = 3)更多(P = 0.53)。
与低功率激光相比,使用高功率激光治疗LPS可显著减少输尿管通路鞘(UAS)、术后支架的使用和手术时间。尽管无统计学意义,但高功率组的SFR即使对于相对较大的结石尺寸也更高,这也反映在这些激光导致的脓毒症相关并发症发生率的降低上。