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低功率与高功率激光在治疗下极结石中的作用:一所大学教学医院的前瞻性非随机研究结果

Role of low- high-power laser in the treatment of lower pole stones: prospective non-randomized outcomes from a university teaching hospital.

作者信息

Pietropaolo Amelia, Mani Mriganka, Hughes Thomas, Somani Bhaskar K

机构信息

Department of Urology, University Hospital Southampton NHS Foundation Trust, Southampton SO153FD, UK.

Department of Urology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

出版信息

Ther Adv Urol. 2022 May 26;14:17562872221097345. doi: 10.1177/17562872221097345. eCollection 2022 Jan-Dec.

Abstract

INTRODUCTION

Ureteroscopy and laser stone fragmentation [flexible ureteroscopy and laser lithotripsy (FURSL)] has risen over the last two decades. Laser technology has also evolved over the time, shifting from low- to high-power lasers with the addition of MOSES technology that allows for 'dusting and pop-dusting' of stones. The aim of the study was to look at the outcomes of FURSL in lower pole stones (LPS) using low- and high-power lasers.

PATIENT AND METHODS

In this study, we compared the outcomes of low-power holmium laser (group A, 20 W) and high-power holmium laser (group B, including both 60 W MOSES integrated system and 100 W lasers) for all patients with LPS treated with laser lithotripsy. Data were collected for patient demographics, stone location, size, pre- and postoperative stent, length of stay, complications and stone free rate (SFR).

RESULTS

A total of 284 patients who underwent FURSL procedure for LPS were analysed (168 group A, 116 group B). Outcomes showed that compared with group A, group B had a higher SFR (91.6% 96.5%,  = 0.13) and shorter operative time (52 38 min,  < 0.001). The median length of stay was <24 h in all groups (day-case procedures). The complication rate was comparable between the two groups but with more infectious complications ( = 7) noted in group A compared with group B ( = 3) ( = 0.53).

CONCLUSION

Compared with low-power laser, the use of high-power laser for LPS significantly reduced the use of ureteral access sheath (UAS), postoperative stent and procedural time. Although non-statistically significant, the SFR was higher in the high-power group even for relatively larger stone sizes, which was also reflected in a reduction of sepsis-related complication rates with these lasers.

摘要

引言

输尿管镜检查和激光碎石术[软性输尿管镜检查和激光碎石术(FURSL)]在过去二十年中得到了广泛应用。随着时间的推移,激光技术也在不断发展,从低功率激光发展到高功率激光,并增加了允许对结石进行“粉末化和弹出式粉末化”的摩西技术。本研究的目的是观察使用低功率和高功率激光治疗下极结石(LPS)的FURSL结果。

患者与方法

在本研究中,我们比较了低功率钬激光(A组,20W)和高功率钬激光(B组,包括60W摩西集成系统和100W激光)对所有接受激光碎石术治疗的LPS患者的治疗效果。收集了患者的人口统计学数据、结石位置、大小、术前和术后支架、住院时间、并发症和结石清除率(SFR)。

结果

共有284例接受FURSL治疗LPS的患者纳入分析(A组168例,B组116例)。结果显示,与A组相比,B组的SFR更高(91.6%对96.5%,P = 0.13),手术时间更短(52对38分钟,P < 0.001)。所有组的中位住院时间均<24小时(日间手术)。两组的并发症发生率相当,但A组(n = 7)的感染性并发症比B组(n = 3)更多(P = 0.53)。

结论

与低功率激光相比,使用高功率激光治疗LPS可显著减少输尿管通路鞘(UAS)、术后支架的使用和手术时间。尽管无统计学意义,但高功率组的SFR即使对于相对较大的结石尺寸也更高,这也反映在这些激光导致的脓毒症相关并发症发生率的降低上。

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