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钬激光碎石联合“爆米花”粉粹术治疗>15mm 大体积尿石症:来自高容量结石中心的 6.5 年前瞻性结果。

Ureteroscopy and lasertripsy with pop dusting using high power holmium laser for large urinary stones > 15 mm: 6.5-year prospective outcomes from a high-volume stone center.

机构信息

Department of Urology, University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, SO16 6YD, UK.

出版信息

World J Urol. 2023 Jul;41(7):1935-1941. doi: 10.1007/s00345-023-04438-4. Epub 2023 May 27.

Abstract

INTRODUCTION

Ureteroscopy and stone lasertripsy (URSL) is a recognized technique for treatment of urinary tract stones. Holmium:Yag laser has been successfully used for this purpose for the last two decades. More lately, pulse modulation with Moses technology and high power lasers have been introduced with the result of faster and more efficient stone lasertripsy. Pop dusting is a two-stage combined treatment using a long pulse Ho:YAG laser, initially in contact mode with the stone 'dusting' (0.2-0.5 J/40-50 Hz) followed by non-contact mode 'pop-dusting' (0.5-0.7 J/20-50 Hz). We wanted to look at the outcomes of lasertripsy for renal and ureteric stones using a high-power laser machine.

METHODS

Over a period of 6.5 years (January 2016-May 2022), we prospectively collected data for patients undergoing URSL for stones larger than 15 mm treated using high power Ho:YAG laser (60W Moses or 100W laser). Patient parameters, stone demographics and outcomes of URSL were analyzed.

RESULTS

A total of 201 patients, underwent URSL for large urinary stones. In 136 patients (61.6%) stones were multiple and the mean single and cumulative stone size was 18 mm and 22.4 mm respectively. A pre- and post-operative stent was placed in 92 (41.4%) and 169 (76%) respectively. The initial and final stone free rate (SFR) were 84.5% and 94% respectively and 10% patients underwent additional procedure to achieve stone free status. 7 (3.9%) complications were recorded, all related to UTI/sepsis, with 6 Clavien II and 1 Clavien IVa complication.

CONCLUSION

Dusting and pop-dusting has shown to be successful and safe with the ability to treat large, bilateral or multiple stones with low retreatment and complication rates.

摘要

介绍

输尿管镜检查和结石激光碎石术(URSL)是治疗尿路结石的公认技术。钬:YAG 激光在过去二十年中已成功用于此目的。最近,随着摩西技术的脉冲调制和高功率激光的引入,实现了更快、更高效的结石激光碎石术。粉末化是一种两阶段联合治疗,使用长脉冲 Ho:YAG 激光,最初以接触模式与结石“粉末化”(0.2-0.5 J/40-50 Hz),然后以非接触模式“粉末化”(0.5-0.7 J/20-50 Hz)。我们想研究使用高功率激光机进行肾结石和输尿管结石激光碎石术的结果。

方法

在 6.5 年的时间里(2016 年 1 月至 2022 年 5 月),我们前瞻性收集了接受 URSL 治疗大于 15mm 结石的患者数据,这些结石使用高功率 Ho:YAG 激光(60W 摩西或 100W 激光)治疗。分析了患者参数、结石特征和 URSL 结果。

结果

共有 201 名患者接受了 URSL 治疗大的尿路结石。在 136 名患者(61.6%)中,结石为多发性,单个和累计结石大小分别为 18mm 和 22.4mm。92 名(41.4%)和 169 名(76%)患者分别放置了术前和术后支架。初始和最终的无结石率(SFR)分别为 84.5%和 94%,10%的患者需要额外的手术才能达到无结石状态。记录了 7 例(3.9%)并发症,均与尿路感染/败血症有关,其中 6 例为 Clavien II 级,1 例为 Clavien IVa 级并发症。

结论

粉末化和爆粉化已被证明是成功和安全的,能够治疗大、双侧或多发性结石,且再治疗和并发症发生率低。

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