Department of Epidemiology and Health Statistics, School of Public Health, Wannan Medical College, Wuhu, China.
Department of Oral Medicine, School of Stomatology, Wannan Medical College, Wuhu, China.
PLoS One. 2022 Jun 2;17(6):e0268773. doi: 10.1371/journal.pone.0268773. eCollection 2022.
Anxiety and depression are great public health concerns among college students. The purpose of this study was to explore whether sleep quality and quality of life (QoL) play mediating roles in anxiety and depression among Chinese college students.
A total of 2757 college students (mean age = 19.07; SD = 1.14) completed the questionnaires, including a brief demographic survey. The 2-item General Anxiety Disorder (GAD-2) and the 2-item Patient Health Questionnaire (PHQ-2) were used to assess the symptoms of anxiety and depression, respectively. And the Pittsburgh Sleep Quality Index (PSQI) and the Short-Form 36 Health Survey (SF-36) were used to evaluate college students' sleep quality and QoL, respectively. Mediation analyses were conducted by using PROCESS macro in the SPSS software.
Anxiety had both direct and indirect effects on depression. Sleep quality and QoL were not only independent mediators in the relationship between anxiety and depression but also chain mediators.
The results of the current study highlight the crucial role of early intervention for depression with a focus on college students with anxiety, more especially, on those with poorer sleep quality and lower QoL.
焦虑和抑郁是大学生面临的重大公共健康问题。本研究旨在探讨睡眠质量和生活质量（QoL）是否在大学生的焦虑和抑郁中起中介作用。
共有 2757 名大学生（平均年龄=19.07；标准差=1.14）完成了问卷，包括简要的人口统计调查。使用 2 项广泛性焦虑障碍（GAD-2）和 2 项患者健康问卷（PHQ-2）分别评估焦虑和抑郁症状。匹兹堡睡眠质量指数（PSQI）和健康调查简表 36 项（SF-36）分别用于评估大学生的睡眠质量和 QoL。使用 SPSS 软件中的 PROCESS 宏进行中介分析。
焦虑对抑郁既有直接影响，也有间接影响。睡眠质量和 QoL 不仅是焦虑和抑郁之间关系的独立中介，也是链式中介。
本研究结果强调了早期干预对抑郁的重要性，尤其是针对那些焦虑、睡眠质量较差和 QoL 较低的大学生。
