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新墨西哥州的居住史与肺癌风险

History of residence and lung cancer risk in New Mexico.

作者信息

Samet J M, Humble C G, Skipper B E, Pathak D R

出版信息

Am J Epidemiol. 1987 May;125(5):800-11. doi: 10.1093/oxfordjournals.aje.a114597.

Abstract

Participants in a population-based case-control study of lung cancer in New Mexico between 1980 and 1982 were asked to identify all locations where they had resided for six months or more. These residential data were coded at the county and state levels and combined with county-level socioeconomic data from the 1910, 1930, 1950, and 1970 decennial censuses to generate indices of time lived in counties or metropolitan areas of different sizes, degrees of urbanization, or extents of employment in manufacturing industries. Urban residence was not associated with employment of male controls in jobs or industries considered to increase lung cancer risk. However, in the non-Hispanic white female controls, urban residence before age 30 years in a county of 500,000 or more residents was associated with a fourfold higher odds ratio for starting to smoke cigarettes. Male and female non-Hispanic controls who had ever lived in more populous counties smoked more cigarettes per day than did those who had not lived in such counties. Residential history patterns were the same in cases and controls; multiple logistic regression showed no consistent associations of the residence history variables with lung cancer risk.

摘要

1980年至1982年间,新墨西哥州一项基于人群的肺癌病例对照研究的参与者被要求列出他们居住过六个月或更长时间的所有地点。这些居住数据按县和州两级进行编码,并与1910年、1930年、1950年和1970年十年一度人口普查的县级社会经济数据相结合,以生成在不同规模、城市化程度或制造业就业程度的县或大都市区居住时间的指数。城市居住与男性对照在被认为会增加肺癌风险的工作或行业中的就业情况无关。然而,在非西班牙裔白人女性对照中,30岁之前居住在居民人数达50万或更多的县与开始吸烟的比值比高出四倍有关。曾居住在人口较多县的非西班牙裔男性和女性对照每天吸烟比未居住在这些县的人更多。病例和对照的居住史模式相同;多元逻辑回归显示居住史变量与肺癌风险没有一致的关联。

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