Hemminki K, Pershagen G
Center for Nutrition and Toxicology, Karolinska Institute, Stockholm, Sweden.
Environ Health Perspect. 1994 Oct;102 Suppl 4(Suppl 4):187-92. doi: 10.1289/ehp.94102s4187.
Epidemiological studies on the effect of urban air pollution on lung cancer were surveyed. Overall, the studies from many countries point to a smoking-adjusted risk in urban areas over countryside areas that is higher by a factor of up to 1.5. The extent to which urban air pollution contributes to this excess remains unknown. Studies on diesel-exposed occupational groups show that urban air pollution may have a causative role in lung cancer. Model calculations on unit risk factors of known human carcinogens were carried out to rank carcinogens according to their current ambient air concentrations.
对城市空气污染对肺癌影响的流行病学研究进行了调查。总体而言,许多国家的研究表明,经吸烟因素调整后,城市地区的肺癌风险比农村地区高,高出幅度可达1.5倍。城市空气污染在这一超额风险中所起的作用程度尚不清楚。对接触柴油的职业群体的研究表明,城市空气污染可能在肺癌中起致病作用。对已知人类致癌物的单位风险因素进行了模型计算,以便根据其当前的环境空气浓度对致癌物进行排名。