Research Center for Environmental Health Technology, Iran University of Medical Sciences, Tehran, Iran.
Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
J Air Waste Manag Assoc. 2022 Sep;72(9):925-934. doi: 10.1080/10962247.2022.2085820. Epub 2022 Jul 19.
Air pollution and health consequences associated with exposure to air pollutants, such as particulate matter, are of serious concerns in societies. Over the recent years, numerous studies have investigated the relation of many diseases with air pollutants. This review used a search strategy to provide the comprehensive information on the relationship between particle matters and osteoporosis. To this end, three search databases were used to find the articles focused on particle matters and osteoporosis. After the screening process, 13 articles related to the purpose of the study were selected and the relevant data were extracted. The results indicated that osteoporosis is significantly associated with PM. However, this association with PM remains unclear. In addition, particle materials indirectly lead to the osteoporosis and bone fractures as a consequence of reduced UV-B, reduced adsorption of vitamin D. Furthermore, they can lead to other diseases by use of drugs with adverse effects on bone health, and creating conditions that may increase the risk of falling in the elderly. This review shows that although more accurate research is needed to determine the mechanism and risk of exposure to particulate matter in the air on bone health, the negative effects of this pollutant on bone mineral density (BMD) are evident.: PM is usually classified by its size or aerodynamic diameter; PM10 denotes particles < 10 µm in diameter; PM2.5 particles are <2.5 µm in diameter. Many epidemiological studies have shown that short-term exposure to PM might reduce lung function. However, short-term effects might be reversible, and the main concern is attributed to long-term exposure. A major public health concern that may be affected by numerous metabolic and even environmental risk factors is osteoporosis. The purpose of this systematic review was to investigate the role of PM in the occurrence or exacerbation of osteoporosis in citizens.
空气污染以及暴露于空气污染物（如颗粒物）对健康造成的后果是社会关注的严重问题。近年来，大量研究已经调查了许多疾病与空气污染物之间的关系。本综述采用搜索策略，提供了关于颗粒物与骨质疏松症之间关系的综合信息。为此，使用了三个搜索数据库来查找专注于颗粒物和骨质疏松症的文章。经过筛选过程，选择了 13 篇与研究目的相关的文章，并提取了相关数据。结果表明，骨质疏松症与 PM 显著相关。然而，这种与 PM 的关联仍不清楚。此外，颗粒物质会通过减少紫外线-B、减少维生素 D 的吸收，间接地导致骨质疏松症和骨折。此外，它们还会通过使用对骨骼健康有不良影响的药物，并创造可能增加老年人跌倒风险的条件，导致其他疾病。本综述表明，尽管需要更精确的研究来确定空气中颗粒物对骨骼健康的机制和风险，但这种污染物对骨矿物质密度（BMD）的负面影响是明显的。PM 通常根据其大小或空气动力学直径进行分类；PM10 表示直径<10µm 的颗粒；PM2.5 颗粒的直径<2.5µm。许多流行病学研究表明，短期暴露于 PM 可能会降低肺功能。然而，短期影响可能是可逆的，主要关注点是长期暴露。一个可能受到许多代谢甚至环境风险因素影响的主要公共卫生关注点是骨质疏松症。本系统综述的目的是调查 PM 在公民中骨质疏松症的发生或恶化中的作用。
