Fanimolky Fatemeh, Amizadeh Maryam
Clinical Research Unit, Shafa Hospital, Kerman University of Medical Science, Kerman, Iran.
Iran J Otorhinolaryngol. 2022 Mar;34(121):89-94. doi: 10.22038/IJORL.2021.52513.2793.
This study aimed to investigate the serum level of vitamin D in patients with ear cholesteatoma.
This cross-sectional study was performed on 62 patients with middle ear cholesteatoma (case group) and 62 patients with simple chronic otitis media (control group). Both groups had the same age (32±1 in the case group and 34±1 in the control group; P=0.973) and gender. Vitamin D serum level was measured in the two groups. Data analysis was conducted using t-test and ANOVA.
According to the statistical analysis, a significant relationship was observed between the serum level of vitamin D and middle ear cholesteatoma (P=0.000). The results showed that the serum level of vitamin D was lower in the case group, compared to the control group.
Vitamin D serum level was lower in the cholesteatoma group. Moreover, it was strongly associated with hearing loss, tinnitus, and vertigo.
本研究旨在调查中耳胆脂瘤患者的血清维生素D水平。
本横断面研究对62例中耳胆脂瘤患者(病例组)和62例单纯慢性中耳炎患者(对照组)进行。两组年龄相同(病例组32±1岁,对照组34±1岁;P = 0.973)且性别相同。测量两组的血清维生素D水平。使用t检验和方差分析进行数据分析。
根据统计分析,观察到血清维生素D水平与中耳胆脂瘤之间存在显著关系(P = 0.000)。结果显示,病例组的血清维生素D水平低于对照组。
胆脂瘤组的血清维生素D水平较低。此外,它与听力损失、耳鸣和眩晕密切相关。