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怀孕母牛的实验性感染:速殖子与卵囊接种后的不同结果

Experimental Infection in Pregnant Cattle: Different Outcomes Between Inoculation With Tachyzoites and Oocysts.

作者信息

Gondim Luís F Pita, McAllister Milton M

机构信息

Department of Anatomy, Pathology and Veterinary Clinics, School of Veterinary Medicine and Animal Science, Federal University of Bahia, Salvador, Brazil.

School of Animal and Veterinary Sciences, The University of Adelaide, Adelaide, SA, Australia.

出版信息

Front Vet Sci. 2022 May 17;9:911015. doi: 10.3389/fvets.2022.911015. eCollection 2022.

DOI:10.3389/fvets.2022.911015
PMID:35656171
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9152450/
Abstract

is a globally distributed abortifacient protozoan of cattle. Experimental infections with in cattle have provided valuable information on host-parasite interaction and immunopathogenesis. Experimental infection of pregnant cows has been reported in about 20 articles, with most studies using cultured parasite tachyzoites as the inoculum. Only three experimental studies have been conducted in pregnant cows using the parasite's oocysts which are shed by dogs, in large part because transmission experiments using oocysts take more time and are more complex and expensive than experiments using tachyzoites. In this minireview, we discuss differences between tachyzoites and oocysts as inocula for experimental infection of pregnant cows, as well as the route animals are inoculated.

摘要

是一种在全球范围内分布的牛堕胎原虫。用其对牛进行实验性感染,为宿主 - 寄生虫相互作用和免疫发病机制提供了有价值的信息。约20篇文章报道了对怀孕母牛的实验性感染,大多数研究使用培养的寄生虫速殖子作为接种物。仅有三项针对怀孕母牛的实验研究使用了由狗排出的寄生虫卵囊,这在很大程度上是因为使用卵囊进行传播实验比使用速殖子的实验耗时更长、更复杂且成本更高。在本综述中,我们讨论了速殖子和卵囊作为怀孕母牛实验性感染接种物的差异,以及动物的接种途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeef/9152450/edf7592e42bc/fvets-09-911015-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeef/9152450/edf7592e42bc/fvets-09-911015-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aeef/9152450/edf7592e42bc/fvets-09-911015-g0001.jpg

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Front Cell Infect Microbiol. 2021 Jun 22;11:684670. doi: 10.3389/fcimb.2021.684670. eCollection 2021.
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An abortion storm in dairy cattle associated with neosporosis in southern Brazil.巴西南部与新孢子虫病相关的奶牛流产风暴。
Rev Bras Parasitol Vet. 2021 May 28;30(2):e001821. doi: 10.1590/S1984-29612021045. eCollection 2021.
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An outbreak of Neospora caninum abortion in a dairy herd from the State of Georgia, United States.
美国乔治亚州一奶牛场爆发新型隐孢子虫流产。
Vet Med Sci. 2021 Jan;7(1):141-147. doi: 10.1002/vms3.346. Epub 2020 Aug 30.
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Foetal death in naive heifers inoculated with Neospora caninum isolate Nc-Spain7 at 110 days of pregnancy.在怀孕110天时接种犬新孢子虫分离株Nc-Spain7的未感染小母牛中发生胎儿死亡。
Exp Parasitol. 2016 Sep;168:62-9. doi: 10.1016/j.exppara.2016.06.009. Epub 2016 Jul 5.
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Neospora caninum infection during early pregnancy in cattle: how the isolate influences infection dynamics, clinical outcome and peripheral and local immune responses.牛妊娠早期的刚地弓形虫感染:分离株如何影响感染动态、临床结局以及外周和局部免疫反应。
Vet Res. 2014 Jan 30;45(1):10. doi: 10.1186/1297-9716-45-10.
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Vet Parasitol. 2014 Jan 17;199(1-2):1-7. doi: 10.1016/j.vetpar.2013.10.006. Epub 2013 Oct 16.
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Neospora caninum NC-6 Argentina induces fetopathy in both serologically positive and negative experimentally inoculated pregnant dams.阿根廷细粒棘球绦虫 NC-6 诱导血清学阳性和阴性的实验接种怀孕母羊发生胎病。
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