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社会经济状况和轻微心理健康问题与抗抑郁药物的联合关联。

Joint association of socioeconomic circumstances and minor mental health problems with antidepressant medication.

机构信息

Department of Public Health, University of Helsinki, Helsinki, Finland.

出版信息

Eur J Public Health. 2022 Aug 1;32(4):535-541. doi: 10.1093/eurpub/ckac048.

Abstract

BACKGROUND

Disadvantageous socioeconomic circumstances and minor mental health problems have both been associated with mental disorders, such as depression, but their joint contribution remains unknown.

METHODS

The Helsinki Health Study baseline survey (2000-02) of 40- to 60-year-old employees was linked with antidepressant medication data from registers of the Social Insurance Institution of Finland. The analyses were made using logistic regression with first prescribed antidepressant medication purchase during a 10-year follow-up as the outcome. Minor mental health problems were measured by the emotional well-being scale of the RAND-36. Odds ratios were calculated for joint association of the lowest quartile of the emotional well-being scale of the RAND-36 and socioeconomic circumstances. Childhood (parental education and childhood economic difficulties), conventional (education, occupational class and income) and material (housing tenure and current economic difficulties) socioeconomic circumstances were examined. This study included 5450 participants.

RESULTS

Minor mental health problems dominated the joint associations. Minor mental health problems were associated with antidepressant medication irrespective of socioeconomic circumstances whereas only low income, current economic difficulties and living in rented housing showed an association without minor mental health problems at baseline. Marital status, working conditions and BMI and health behaviours had only minimal contributions to the associations.

CONCLUSIONS

Minor mental health problems were consistently and strongly associated with antidepressant medication and dominated the joint associations with socioeconomic circumstances. Paying attention to minor mental health problems might help prevent mental disorders such as depression.

摘要

背景

不利的社会经济环境和轻微的心理健康问题都与抑郁症等精神障碍有关,但它们的共同作用尚不清楚。

方法

将赫尔辛基健康研究基线调查(2000-02 年)中的 40-60 岁员工与芬兰社会保险机构的抗抑郁药物登记处的数据相关联。使用逻辑回归进行分析,以 10 年随访期间首次开具的抗抑郁药物购买为结果。使用 RAND-36 的情绪健康量表测量轻微的心理健康问题。计算了 RAND-36 情绪健康量表最低四分位数和社会经济状况联合关联的优势比。检查了童年(父母教育和童年经济困难)、传统(教育、职业阶层和收入)和物质(住房保有和当前经济困难)社会经济状况。这项研究包括 5450 名参与者。

结果

轻微的心理健康问题主导了联合关联。轻微的心理健康问题与抗抑郁药物的使用有关,而不论社会经济状况如何,而只有低收入、当前经济困难和租房居住在没有轻微心理健康问题的情况下与抗抑郁药物的使用有关。婚姻状况、工作条件和 BMI 以及健康行为对关联的贡献很小。

结论

轻微的心理健康问题与抗抑郁药物的使用始终密切相关,并主导了与社会经济状况的联合关联。关注轻微的心理健康问题可能有助于预防抑郁症等精神障碍。

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