Mittal V K, Bodzin J H
Am J Surg. 1980 Sep;140(3):396-9. doi: 10.1016/0002-9610(80)90176-2.
Primary malignant tumors of the small bowel are uncommon and are often diagnosed at an advanced stage. A 10 year survey (1967 to 1977) of the clinical records at one hospital revealed 39 cases of primary malignant tumors of the small bowel. The most common symptoms were abdominal pain (89.7 percent) and weight loss (77 percent). Six patients presented with complications of enterovesical fistula, bleeding and perforation. Preoperative diagnosis was suspected in 27 cases (69.2 percent). Adenocarcinoma was the most common tumor, followed by carcinoid tumor, lymphoma, leiomyosarcoma and melanoma. The treatment of choice was surgical resection whenever possible. Curative resection was attempted in 25 cases. Adjuvant radiotherapy and chemotherapy was used in four patients with lymphoma. Twenty-seven patients (69.2 percent) are alive from 1 to 6 years after diagnosis and treatment. The 5 year survival rate is 35 percent. Earlier diagnosis is essential if the prognosis for patients with small bowel malignancy is to be improved.
小肠原发性恶性肿瘤并不常见,且常于晚期才得以诊断。一家医院对1967年至1977年期间的临床记录进行的为期10年的调查显示,有39例小肠原发性恶性肿瘤。最常见的症状是腹痛(89.7%)和体重减轻(77%)。6例患者出现肠膀胱瘘、出血和穿孔等并发症。27例(69.2%)患者术前被怀疑患有该病。腺癌是最常见的肿瘤,其次是类癌、淋巴瘤、平滑肌肉瘤和黑色素瘤。治疗的首选方法是尽可能进行手术切除。25例患者尝试进行根治性切除。4例淋巴瘤患者接受了辅助放疗和化疗。27例患者(69.2%)在诊断和治疗后存活了1至6年。5年生存率为35%。若要改善小肠恶性肿瘤患者的预后,早期诊断至关重要。