University of Pristina-Kosovska Mitrovica, Faculty of Medicine, Kosovska Mitrovica, Serbia.
Clinic for Infectious Diseases, Clinical Centre of Kosovska Mitrovica, Kosovska Mitrovica Serbia.
J Infect Dev Ctries. 2022 May 30;16(5):850-856. doi: 10.3855/jidc.13055.
Measles is among the most contagious and vaccine-preventable respiratory diseases. The aim of this research was to describe the socio-demographic profile, clinical manifestations and laboratory parameters of measles patients hospitalized at Kosovska Mitrovica Clinical Centre during the 2017-2019 outbreak.
The prospective study included all patients that had contracted measles (107) who were hospitalized at Kosovska Mitrovica Clinical Centre during the outbreak. All complications that led to hospitalization were analyzed and the frequencies of complications with respect to patient age and vaccination status were recorded.
More than half (51%) of the patients were unvaccinated. Patients' age varied statistically significantly with respect to vaccination status. Pneumonia was noted in 65% of the patients from the younger age group, compared to 32% of adults, and this difference was statistically significant. Hepatitis was a significantly more frequent complication in adults, affecting 36% of measles patients in this age group, compared to only 7% of those aged below 18 years. In the unvaccinated group, 71% pneumonia frequency was noted, compared to 11% and 35% in the vaccinated and unknown vaccination status groups, respectively. The differences in frequencies based on vaccination status were statistically significant.
Most hospitalized patients were unvaccinated. Complications showed a significant difference with respect to the age and vaccination status of patients. Therefore, it is necessary to carry out continuous health promotion activities to raise awareness among the entire population of the importance and need for vaccination of children against measles, but also adults who have not been previously vaccinated.
麻疹是最具传染性和可通过疫苗预防的呼吸道疾病之一。本研究旨在描述 2017-2019 年期间在科索夫斯卡米特罗维察临床中心爆发麻疹期间住院的麻疹患者的社会人口学特征、临床表现和实验室参数。
这项前瞻性研究包括在疫情期间在科索夫斯卡米特罗维察临床中心住院的所有(107 例)感染麻疹的患者。分析了导致住院的所有并发症,并记录了并发症的发生频率与患者年龄和疫苗接种状态的关系。
超过一半(51%)的患者未接种疫苗。患者的年龄与疫苗接种状态有统计学上的显著差异。年龄较小的患者中,65%患有肺炎,而成年人中只有 32%,差异具有统计学意义。在成年人中,肝炎是一种更常见的并发症,在该年龄组的麻疹患者中,有 36%的患者患有肝炎,而在 18 岁以下的患者中,只有 7%的患者患有肝炎。在未接种疫苗的患者中,71%的患者出现肺炎,而接种疫苗和未知接种状态的患者中,分别为 11%和 35%。基于疫苗接种状态的频率差异具有统计学意义。
大多数住院患者未接种疫苗。并发症与患者的年龄和疫苗接种状态存在显著差异。因此,有必要开展持续的健康促进活动,提高全民对儿童接种麻疹疫苗的重要性和必要性的认识,同时也要提高未接种过疫苗的成年人的认识。