Graduation Program in Dentistry, School of Medicine and Life Sciences, Pontifícia Universidade Católica Do Paraná, 1155 Imaculada Conceição, Curitiba, PE, 80215-901, Brazil.
Support Care Cancer. 2022 Nov;30(11):8667-8678. doi: 10.1007/s00520-022-07168-2. Epub 2022 Jun 3.
The aim of this systematic review was to investigate the clinical effectiveness of glass ionomer cements (GICs) compared to other restorative materials in the treatment of radiation-related caries.
Two independent researchers searched literature databases (PubMed, Scopus, Web of Science, Cochrane Library, Lilacs/BBO) and the grey literature to identify clinical trials that compared GICs with other restorative materials for the treatment of radiation-related caries. The clinical criteria considered for the performance of the restorations were based on the parameters of marginal adaptation/anatomical form, secondary caries, retention, and cumulative failures of the restorations. The methodological quality and risk of bias were evaluated using the Cochrane Collaboration tool.
From a total of 511, only four articles fulfilled the inclusion criteria. Conventional GIC restorations presented higher marginal adaptation failures than the resin-modified glass ionomer cements (RM-GICs) and composite restorations in all of the follow-up periods. Secondary caries was not observed in conventional GIC restorations throughout the follow-up periods, in three out of four of the included studies. RM-GICs and composite restorations showed significantly lower cumulative failure rates than conventional GICs at 6-, 12-, and 18-month follow-ups.
Due to insufficient scientific evidence, it was not possible to conclude that GICs are more effective than other restorative materials for the treatment of radiation-related caries.
本系统评价旨在研究玻璃离子水门汀（GIC）与其他修复材料在治疗放射性龋方面的临床疗效。
两名独立的研究人员检索了文献数据库（PubMed、Scopus、Web of Science、Cochrane Library、Lilacs/BBO）和灰色文献，以确定比较 GIC 与其他修复材料治疗放射性龋的临床试验。修复体性能考虑的临床标准基于边缘适应性/解剖形态、继发龋、保留率和修复体累积失败的参数。使用 Cochrane 协作工具评估方法学质量和偏倚风险。
在总共 511 篇文章中，只有 4 篇文章符合纳入标准。在所有随访期内，传统 GIC 修复体的边缘适应性失败率均高于树脂改性玻璃离子水门汀（RM-GIC）和复合修复体。在所有的随访期内，传统 GIC 修复体均未观察到继发龋。RM-GIC 和复合修复体在 6、12 和 18 个月的随访中显示出明显低于传统 GIC 的累积失败率。
由于科学证据不足，无法得出 GIC 比其他修复材料更有效地治疗放射性龋的结论。
