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在线药物评估工具(MedReview)的开发、验证与评估

Development, validation and evaluation of an online medication review tool (MedReview).

作者信息

Thiruchelvam Kaeshaelya, Hasan Syed Shahzad, Pudmenzky Alex, Se Wong Pei, Kairuz Therese

机构信息

School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.

School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, New South Wales, Australia.

出版信息

PLoS One. 2022 Jun 3;17(6):e0269322. doi: 10.1371/journal.pone.0269322. eCollection 2022.

Abstract

OBJECTIVES

To develop, validate and evaluate a computerized clinical decision support system (MedReview) that aids medication reviewers with pharmacological decision-making.

METHODS

This study included three phases; the development phase included computerizing a consolidated medication review algorithm (MedReview), followed by validation and evaluation of MedReview and responding to a web-based survey designed using patient scenarios. Participants had to be 'fully registered' with the Malaysian Pharmacy Board and work full-time at a community pharmacy.

RESULTS

MedReview was developed as a web app. It was validated among 100 community pharmacists from May-July 2021 using the Technology Acceptance Model (TAM). There was acceptable content validity and fair inter-rater agreement, and good convergent and discriminant validity. Exploratory factor analysis resulted in five domains to determine the attitude of pharmacists about using MedReview: perceived ease of use, perceived usefulness, intention to use, trust, and personal initiatives and characteristics; the total variance explained by five factors was 76.36%. The survey questionnaire had a high overall reliability value of 0.96. Evaluation of MedReview was based on mean scores of survey items. Of all items included in the survey, the highest mean score (out of 7) was achieved for 'I could use MedReview if it is meaningful/relevant to my daily tasks' (5.78 ± 1.10), followed by 'I could use MedReview if I feel confident that the data returned by MedReview is reliable' (5.77 ± 1.21), and 'I could use MedReview if it protects the privacy of its users' (5.73 ± 1.20).

CONCLUSION

Community pharmacists generally had a positive attitude towards MedReview. They found that MedReview is trustworthy and they had the intention to use it when conducting medication reviews. The adaptation of the TAM in the survey instrument was reliable and internally valid.

摘要

目的

开发、验证并评估一个计算机化临床决策支持系统(MedReview),以协助药物审查人员进行药理决策。

方法

本研究包括三个阶段;开发阶段包括将综合药物审查算法(MedReview)计算机化,随后对MedReview进行验证和评估,并对基于患者场景设计的网络调查做出回应。参与者必须在马来西亚药剂师委员会“完全注册”,并在社区药房全职工作。

结果

MedReview被开发为一个网络应用程序。2021年5月至7月期间,使用技术接受模型(TAM)在100名社区药剂师中对其进行了验证。内容效度可接受,评分者间一致性尚可,收敛效度和区分效度良好。探索性因素分析得出五个领域来确定药剂师对使用MedReview的态度:感知易用性、感知有用性、使用意图、信任以及个人主动性和特征;五个因素解释的总方差为76.36%。调查问卷的总体信度值较高,为0.96。基于调查项目的平均得分对MedReview进行评估。在调查包含的所有项目中,“如果MedReview对我的日常任务有意义/相关,我可以使用它”(5.78±1.10)的平均得分(满分7分)最高,其次是“如果我确信MedReview返回的数据可靠,我可以使用它”(5.77±1.21),以及“如果MedReview保护其用户的隐私,我可以使用它”(5.73±1.20)。

结论

社区药剂师对MedReview总体持积极态度。他们发现MedReview是值得信赖的,并且在进行药物审查时有使用它的意图。调查工具中对TAM的改编是可靠的且内部有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9d7/9165870/576bb496f9ce/pone.0269322.g001.jpg

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