Harrington Cara Íosa, O'Keeffe Nicholas, Lennon Paul
Department of Otolaryngology/Head & Neck Surgery, St James' Hospital, Dublin 8, Ireland.
Department of Otolaryngology/Head & Neck Surgery, St James' Hospital, Dublin 8, Ireland.
Int J Surg Case Rep. 2022 May;94:107089. doi: 10.1016/j.ijscr.2022.107089. Epub 2022 Apr 18.
Carotid artery blowout syndrome is a rare complication of head and neck cancer treatment. It defines a rupture of the carotid artery wall through vessel wall necrosis. This is typically precipitated by radiotherapy, direct tumour invasion, or a combination of these factors. We describe a rare case of three consecutive carotid artery blowouts in a head and neck cancer patient.
A 58-year-old man with a history of T3NO hypopharyngeal squamous cell carcinoma (SCC) treated with chemotherapy and radiation presented with a four-month history of progressive dysphagia and right sided neck pain. Flexible nasendoscopy revealed laryngeal oedema and slough. A panendoscopy and biopsy showed no evidence of tumour recurrence. The patient was discharged and represented with worsening dyspnoea. He subsequently experienced a large volume hemorrhage necessitating ligation of his right external carotid artery. He underwent pharyngolaryngectomy indicated due to the extent of laryngeal radiation necrosis. Thereafter he suffered two additional acute carotid bleeds from his right common carotid necessitating ligation in theatre.
This case report illustrates the key issues to be considered in patients with locally advanced hypopharyngeal squamous cell carcinoma and subsequent management of acute carotid blowout syndrome, which without prompt management, can be fatal.
颈动脉破裂综合征是头颈癌治疗中一种罕见的并发症。它定义为颈动脉壁因血管壁坏死而破裂。这通常由放疗、肿瘤直接侵犯或这些因素共同作用引发。我们描述了一例头颈癌患者连续三次发生颈动脉破裂的罕见病例。
一名58岁男性,有T3NO下咽鳞状细胞癌病史,接受过化疗和放疗,出现进行性吞咽困难和右侧颈部疼痛4个月。可弯曲鼻内镜检查显示喉部水肿和溃疡。全面内镜检查及活检未发现肿瘤复发迹象。患者出院后再次就诊,呼吸困难加重。随后他经历了大量出血,需要结扎右侧颈外动脉。由于喉部放射性坏死的程度,他接受了咽喉切除术。此后,他右侧颈总动脉又发生了两次急性出血,需要在手术室进行结扎。
本病例报告阐述了局部晚期下咽鳞状细胞癌患者应考虑的关键问题以及急性颈动脉破裂综合征的后续处理,若不及时处理,该综合征可能致命。