Galzignato Pier Francesco, Chirumbolo Salvatore, Cestaro Walter, Scapinello Antonio, Bertossi Dario, Nocini Riccardo
Department of Surgery, Dentistry, Paediatrics and Gynaecology-Unit of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy.
Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Int J Surg Case Rep. 2022 May;94:107165. doi: 10.1016/j.ijscr.2022.107165. Epub 2022 May 4.
Schwannomas are benign neurogenic neoplasms with an uncommon involvement of the nasal cavity and paranasal sinus, which usually appear as a painless formation. We report two cases of nasal schwannoma that was successfully treated by surgical excision with satisfactory functional outcomes. The aim of this study is to discuss the clinical assessment and imaging, (CT, MRI) differential diagnosis, histological examination, surgical approaches of this rarely encountered neoplasm in the sinus-nasal area.
Case 1: a 53 years-old Caucasian male, hospitalized in the ENT Department with a 5-month progressive history of right nasal obstruction without epistaxis was diagnosed as a Schwannoma following clinical, histology and ENT endoscopy examination. Case 2: a 45 years-old Caucasian male with asymptomatic swelling arising 4 months before in the nasal tip area with progressive nasal deformity, diagnosed as a schwannoma and analyzed with MRI.
Case 1: The patient had an uneventful post-operative course and a follow-up examination at 36 months showed no recurrence of the neoplasm with satisfactory functional result. Case 2: The patient had an uneventful post-operative course and a follow-up examination at 5 years showed no recurrence of the neoplasm and satisfactory aesthetic result.
Schwannomas arising from sinonasal area are extremely rare, painless and with slow-growing evolution. The surgical option and histologic analysis are mandatory for a correct diagnosis.
施万细胞瘤是一种良性神经源性肿瘤，很少累及鼻腔和鼻窦，通常表现为无痛性肿物。我们报告两例鼻腔施万细胞瘤，通过手术切除成功治疗，功能预后良好。本研究的目的是探讨鼻窦-鼻腔区域这种罕见肿瘤的临床评估、影像学检查（CT、MRI）、鉴别诊断、组织学检查及手术方法。
病例1：一名53岁的白种男性，因右侧鼻塞进行性加重5个月入住耳鼻喉科，无鼻出血，经临床、组织学及耳鼻喉内镜检查后诊断为施万细胞瘤。病例2：一名45岁的白种男性，鼻尖区4个月前出现无症状肿胀并伴有进行性鼻畸形，诊断为施万细胞瘤并进行了MRI分析。
病例1：患者术后恢复顺利，36个月的随访检查显示肿瘤无复发，功能结果满意。病例2：患者术后恢复顺利，5年的随访检查显示肿瘤无复发且美学效果满意。
鼻窦区域发生的施万细胞瘤极为罕见，无痛且生长缓慢。手术选择和组织学分析对于正确诊断至关重要。
