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一例酷似恶性肠壁增厚的盲肠炎性肌纤维母细胞瘤病例报告

A case report of inflammatory myofibroblastic tumor of cecum mimicking malignant wall thickening.

作者信息

Bettach H, El Bouardi N, Haloua M, Alami B, Boubbou M, Chbani L, Maâroufi M, Lamrani M Y Alaoui

机构信息

Radiology Department, CHU Hassan II Fez, Morocco; Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdellah University, Fez, Morocco.

Radiology Department, CHU Hassan II Fez, Morocco; Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdellah University, Fez, Morocco.

出版信息

Int J Surg Case Rep. 2022 May;94:107166. doi: 10.1016/j.ijscr.2022.107166. Epub 2022 May 4.

Abstract

INTRODUCTION

Inflammatory myofibroblastic tumors (IMT) are an uncommon mesenchymal solid tumor commonly documented in children and young adults (Kim et al., 2012 [1]). Cecum is a rare location of this entity, may simulating a malignant tumor process.

PRESENTATION OF CASE

A 71 year old patient was admitted for pain in the right iliac fossa with chronic constipation evolving for two months associated with weight loss. As a diagnosic step, an abdominal computed tomography (CT) scan was performed showing a thickening of the cecal wall. There was no regional or distant metastasis. During a colonoscopy, many biopsies have been returned to a non-specific chronic colitis; as a result, the IMT of the cecum was confirmed pathologically after ilio-coecal resection.

DISCUSSION

IMT is difined as a solid mesenchymal tumor basically affects the soft parts as well as the visceral organs. The litterature show that frequent localisations are pulmonary and intra-orbital (Krzysztof Siemion et al., 23 February 2022); therefore, the cecal location is very rare may mimic a malignant tumor (Mauricio Gonzalez-Urquijo et al., January 20, 2020), It is worth recalling that the imaging outcomes are polymorphic and inconclusive; in addition, Surgical excision is the treatment of choice for IMT (Alireza Mirshemirani et al., Dec 2011) and the histopathology is still required for the final diagnosis.

CONCLUSION

Radiologic features of IMT present a diagnostic challenge to the radiologist; also, mimic malignancy may lead to unnecessary investigations.

摘要

引言

炎性肌纤维母细胞瘤(IMT)是一种罕见的间叶性实体肿瘤,常见于儿童和年轻人(Kim等人,2012 [1])。盲肠是该实体瘤的罕见发病部位,可能会模拟恶性肿瘤过程。

病例介绍

一名71岁患者因右下腹疼痛、慢性便秘持续两个月并伴有体重减轻入院。作为诊断步骤,进行了腹部计算机断层扫描(CT),显示盲肠壁增厚。无区域或远处转移。在结肠镜检查期间,多次活检结果均为非特异性慢性结肠炎;因此,在进行回盲部切除术后,病理证实为盲肠IMT。

讨论

IMT被定义为一种实体间叶性肿瘤,主要影响软组织和内脏器官。文献表明,常见的发病部位是肺部和眶内(Krzysztof Siemion等人,2022年2月23日);因此,盲肠部位非常罕见,可能会模仿恶性肿瘤(Mauricio Gonzalez-Urquijo等人,2020年1月20日)。值得一提的是,影像学表现具有多态性且无定论;此外,手术切除是IMT的首选治疗方法(Alireza Mirshemirani等人,2011年12月),最终诊断仍需组织病理学检查。

结论

IMT的放射学特征给放射科医生带来了诊断挑战;此外,模仿恶性肿瘤可能导致不必要的检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f277/9097691/17da59bcea77/gr1.jpg

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