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高海拔地区的印度居民是否更容易感染新冠病毒?研究结果及其对研究和政策的潜在影响。

Are High-Altitude Residents More Susceptible to Covid-19 in India? Findings and Potential Implications for Research and Policy.

机构信息

Independent Research, Siliguri, India.

Global Development Institute, 5292University of Manchester, Manchester, UK.

出版信息

Int J Health Serv. 2022 Oct;52(4):455-469. doi: 10.1177/00207314221104887. Epub 2022 Jun 5.

DOI:10.1177/00207314221104887
PMID:35658732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9171131/
Abstract

In this paper, we study the incidence of COVID-19 and the associated fatality with altitude using high frequency, district level data from India. To understand the implications of the nationwide lockdown after the outbreak, we use data for about four months- two from the lockdown period starting from March 25 till May 31, 2020 and about two months after unlocking was initiated (June 1-July 26, 2020). The multivariate regression result indicates slower growth in average rate of infection during the lockdown period in hilly regions, the gains of which attenuated after the unlocking was initiated. Despite these early gains, the rate of fatalities is significantly higher during the lockdown period in comparison to the plains. The findings remain robust to multiple alternative specifications and methods including one that accounts for confounding possibilities via unobservable and provides consistent estimates of bias adjusted treatment effects. The evidence supports the need for provisioning of public health services and infrastructure upgradation, especially maintenance of adequate stock of life support devices, in high altitude regions. It also underscores the necessity for strengthening and revising the existing Hill Areas Development Programme and integrating important aspects of public health as part of this policy.

摘要

在本文中,我们使用来自印度的高频、地区级数据研究了 COVID-19 的发病率以及与海拔高度的关系。为了了解疫情爆发后全国封锁的影响,我们使用了大约四个月的数据——封锁期间的两个月(从 2020 年 3 月 25 日至 5 月 31 日)和解锁开始后的两个月(2020 年 6 月 1 日至 7 月 26 日)。多元回归结果表明,在丘陵地区,封锁期间平均感染率的增长速度较慢,而解锁后这种增长速度有所减弱。尽管有这些早期的收益,但与平原地区相比,封锁期间的死亡率明显更高。这些发现通过不可观察的因素来解释混杂可能性,并提供了一致的、经过偏差调整的治疗效果估计值,对于多种替代规范和方法仍然是稳健的。该证据支持在高海拔地区提供公共卫生服务和基础设施升级的必要性,特别是维持足够数量的生命支持设备库存。它还强调了加强和修订现有的山区发展计划以及将公共卫生的重要方面纳入该政策的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/6d7b5a4e2926/10.1177_00207314221104887-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/8e5adffbb4e0/10.1177_00207314221104887-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/b97bad2e0b75/10.1177_00207314221104887-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/797fbba388e7/10.1177_00207314221104887-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/b94b21b19800/10.1177_00207314221104887-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/a147f3c42155/10.1177_00207314221104887-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/e63f1447bfa7/10.1177_00207314221104887-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/6d7b5a4e2926/10.1177_00207314221104887-fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/8e5adffbb4e0/10.1177_00207314221104887-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/b97bad2e0b75/10.1177_00207314221104887-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/797fbba388e7/10.1177_00207314221104887-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/b94b21b19800/10.1177_00207314221104887-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/a147f3c42155/10.1177_00207314221104887-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/e63f1447bfa7/10.1177_00207314221104887-fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9113/9449435/6d7b5a4e2926/10.1177_00207314221104887-fig7.jpg

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本文引用的文献

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COVID mortality in India: National survey data and health facility deaths.印度的 COVID 死亡率:全国调查数据和卫生机构死亡人数。
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Contrast in utilization of maternal and child health services between Himalayan region and rest of India: Evidence from National Family Health Survey (2015-16).喜马拉雅地区与印度其他地区妇幼保健服务利用的对比:基于全国家庭健康调查(2015-16 年)的证据。
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An interrupted time series analysis of the lockdown policies in India: a national-level analysis of COVID-19 incidence.
印度封锁政策的中断时间序列分析:COVID-19 发病率的国家级分析。
Health Policy Plan. 2021 Jun 3;36(5):620-629. doi: 10.1093/heapol/czab027.
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COVID-19 and urban vulnerability in India.COVID-19与印度城市的脆弱性
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J Travel Med. 2020 Nov 9;27(7). doi: 10.1093/jtm/taaa128.
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Lower Incidence of COVID-19 at High Altitude: Facts and Confounders.高海拔地区 COVID-19 发病率较低:事实与混杂因素。
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