161821Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA.
Pathology and Laboratory Medicine Institute, 2569Cleveland Clinic, Cleveland, OH, USA.
Pediatr Dev Pathol. 2022 Sep-Oct;25(5):558-561. doi: 10.1177/10935266221106910. Epub 2022 Jun 4.
Angiomyxoma of the umbilical cord is a rare benign vascular malformation with potential for fetal morbidity and mortality. Gross and histologic features of this lesion are identical to those described as "hemangioma," however "angiomyxoma" is a preferable term as current practice restricts the term "hemangioma" to infantile capillary proliferations that express glucose transporter 1. Here we describe the case of an umbilical cord angiomyxoma with associated pseudocysts diagnosed after delivery at 33 weeks. It presented as a heterogeneous-appearing mass near the fetal cord insertion and mimicked serious fetal anomalies throughout gestation. We found fetal MRI helpful for monitoring this lesion, narrowing the differential, and informing management. Proximity to the fetal end of the cord and uncertainty about diagnosis also required surgical resection of the mass after delivery with umbilicoplasty.
脐带血管黏液瘤是一种罕见的良性血管畸形，可能导致胎儿患病和死亡。该病变的大体和组织学特征与描述为“血管瘤”的特征相同，但“血管黏液瘤”是一个更合适的术语，因为目前的实践将“血管瘤”一词限制为表达葡萄糖转运蛋白 1 的婴儿毛细血管增生。在此，我们描述了一例在 33 周分娩后诊断的伴有假性囊肿的脐带血管黏液瘤。它表现为胎儿脐带插入处附近的不均匀肿块，在整个妊娠期均模仿严重的胎儿异常。我们发现胎儿 MRI 有助于监测该病变，缩小鉴别范围并指导管理。肿块靠近脐带的胎儿端，且诊断不确定，因此还需要在分娩后进行脐带成形术切除肿块。
