Department of Novel Food Production and Characterization, Institute of Food Science Research (CIAL) (CSIC-UAM), Nicolás Cabrera 9, 28049 Madrid, Spain; Sección Departamental de Ciencias de la Alimentación, Facultad de Ciencias, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Department of Novel Food Production and Characterization, Institute of Food Science Research (CIAL) (CSIC-UAM), Nicolás Cabrera 9, 28049 Madrid, Spain; Sección Departamental de Ciencias de la Alimentación, Facultad de Ciencias, Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Food Chem. 2022 Oct 30;392:133197. doi: 10.1016/j.foodchem.2022.133197. Epub 2022 May 10.
This study aimed to selectively enrich stearidonic acid (SDA) together with γ-linolenic acid (GLA) in Echium plantagineum oil by urea complexation. The complexation process at room temperature was carried out replacing common organic solvents, such as hexane and ethanol, by alternative compounds, included in Green Solvent and Food Grade categories, adapting this process towards the principles of Green Chemistry. This substitution was also intended to avoid the generation of the toxic compound ethyl carbamate. Among all the solvents studied, the mixture propionic acid and α-pinene provided the best results, leading to a final product comprised of ∼99% of PUFA, with ∼45% SDA (∼14% in the original oil), and without apparition of ethyl carbamate. The procedure was tested on other raw materials (salmon and microalgae oils). The solvent was efficiently recuperated from the liquid phase (∼87% recovery) and reutilized once with almost identical results.
本研究旨在通过尿素络合法选择性地富集厚叶补血草油中的 stearidonic acid（SDA）和 γ-linolenic acid（GLA）。室温下的络合过程替代了常用的有机溶剂，如己烷和乙醇，采用了包括在绿色溶剂和食品级别的替代化合物，使这一过程适应绿色化学的原则。这种替代还旨在避免生成有毒化合物氨基甲酸乙酯。在所研究的所有溶剂中，丙酸和 α-蒎烯的混合物提供了最佳结果，最终产物包含约 99%的多不饱和脂肪酸，其中 SDA 约占 45%（原始油中约占 14%），且没有氨基甲酸乙酯的出现。该方法在其他原料（三文鱼油和微藻油）上进行了测试。溶剂从液相中高效回收（约 87%的回收率），并可重复使用，几乎得到相同的结果。
