士兵接种天花疫苗后出现肢端丘疹水疱疹。

Acral Papulovesicular Eruption in a Soldier Following Smallpox Vaccination.

机构信息

Drs. Lenz and Fillman are from the San Antonio Military Medical Center, Texas. Dr. Lenz is from the Department of Dermatology, and Dr. Fillman is from the Department of Dermatopathology. Dr. Grenier is from the Carl R. Darnall Army Medical Center Dermatology Clinic, Fort Hood, Texas.

出版信息

Cutis. 2022 Apr;109(4):194-196. doi: 10.12788/cutis.0502.

DOI:10.12788/cutis.0502

PMID:35659837

Abstract

Smallpox vaccination is associated with several potential cutaneous adverse reactions, ranging from benign self-limited hypersensitivity reactions to life-threatening eczema vaccinatum and progressive vaccinia. Acral papulovesicular eruption is a distinct presentation that has been described in US Military service members following vaccination with the second-generation smallpox vaccine (ACAM2000, Sanofi Pasteur Biologics Co). We describe a case of this unique cutaneous eruption and review previously described cutaneous adverse events associated with smallpox vaccination.

摘要

天花疫苗接种与几种潜在的皮肤不良反应有关，从良性自限性过敏反应到危及生命的牛痘湿疹和进行性牛痘。肢端水疱性疹是一种独特的表现，在美国军人接种第二代天花疫苗（ACAM2000，赛诺菲巴斯德生物制品公司）后有描述。我们描述了一例这种独特的皮肤疹，并回顾了以前描述的与天花疫苗接种相关的皮肤不良事件。