Columbia University Irving Medical Center, United States of America.
Columbia University Irving Medical Center, United States of America; Columbia University, United States of America.
Best Pract Res Clin Anaesthesiol. 2022 May;36(1):107-121. doi: 10.1016/j.bpa.2022.02.003. Epub 2022 Feb 10.
Preeclampsia is a severe manifestation of maternal hypertensive disease affecting 2-8% of pregnancies. The disease places women at risk of women at risk of life-threatening events, including cerebral hemorrhage, pulmonary edema, acute kidney injury, hepatic failure or rupture, disseminated intravascular coagulation, eclampsia, and placental abruption. In addition to the maternal disease burden, increased fetal morbidity and mortality occurs due to iatrogenic preterm delivery, fetal growth restriction, and placental abruption. Magnesium therapy for seizure prophylaxis and blood pressure control to limit cardiovascular and cerebrovascular morbidity are the cornerstone of treatment. Interdisciplinary planning and management are crucial to optimizing patient outcomes.
子痫前期是一种严重的孕妇高血压疾病,影响 2-8%的妊娠。该疾病使女性面临危及生命的事件的风险,包括脑出血、肺水肿、急性肾损伤、肝衰竭或破裂、弥散性血管内凝血、子痫和胎盘早剥。除了母体疾病负担外,由于医源性早产、胎儿生长受限和胎盘早剥,胎儿发病率和死亡率也会增加。镁治疗用于预防抽搐和控制血压以限制心血管和脑血管发病率是治疗的基石。多学科规划和管理对于优化患者结局至关重要。