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椎管内分娩镇痛:除了阿片类药物之外,椎管内辅助药物是否还有用武之地?

Neuraxial labor analgesia: is there a place for neuraxial adjuvants beyond opioids.

机构信息

Department of Cardiovascular Sciences, KULeuven and Department of Anaesthesiology, UZLeuven, Herestraat 49, 3000 Leuven, Belgium.

Department of Anaesthesiology, GZA Hospitals, Antwerp, Belgium.

出版信息

Best Pract Res Clin Anaesthesiol. 2022 May;36(1):31-36. doi: 10.1016/j.bpa.2022.04.006. Epub 2022 Apr 29.

Abstract

Neuraxial labor analgesia is considered the gold standard technique for analgesia. Ideally, a good neuraxial technique uses dilute local anesthetic solutions to produce effective pain relief with no or minimal motor impairment. Adjuvant drugs that are co-administered with the local anesthetic either epidurally or intrathecally are useful in achieving this goal. The current review focuses on the effectivity and side-effect profile of various commonly used or tested adjuvants.

摘要

椎管内分娩镇痛被认为是镇痛的金标准技术。理想情况下,一种好的椎管内技术使用稀释的局部麻醉剂溶液,以达到有效止痛而无或最小的运动障碍。与局部麻醉剂一起硬膜外或鞘内给予的辅助药物有助于实现这一目标。本综述重点介绍了各种常用或经过测试的辅助药物的有效性和副作用概况。

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