Bowmer M I, Nsanze H, D'Costa L J, Dylewski J, Fransen L, Piot P, Ronald A R
Antimicrob Agents Chemother. 1987 Jan;31(1):67-9. doi: 10.1128/AAC.31.1.67.
Men with genital ulcers that were culture positive for Haemophilus ducreyi were treated with intramuscular ceftriaxone and randomized to three different dose regimens. All but 1 of 50 men treated with 1 g of intramuscular ceftriaxone were cured. Similarly, 0.5 and 0.25 g cured 43 of 44 men and 37 of 38 men, respectively. A single dose of 250 mg of intramuscular ceftriaxone is an effective treatment for chancroid.
生殖器溃疡培养出杜克雷嗜血杆菌呈阳性的男性患者接受了肌内注射头孢曲松治疗,并被随机分为三种不同剂量方案。50名接受1克肌内注射头孢曲松治疗的男性中,除1人外全部治愈。同样,0.5克和0.25克剂量分别治愈了44名男性中的43名和38名男性中的37名。单剂量250毫克肌内注射头孢曲松是治疗软下疳的有效方法。