Zhang Wei-Tong, Wang Ya-Bing, Ang Yi, Wang Hui-Zhen, Li Yong-Xiang
Department of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei 23000, Anhui Province, China.
Department of Breast Surgery, Yijishan Hospital of Wannan Medical College, Wuhu 241000, Anhui Province, China.
World J Clin Cases. 2022 May 16;10(14):4648-4653. doi: 10.12998/wjcc.v10.i14.4648.
Pleomorphic adenoma (PA) is the most common type of salivary gland tumor, and its common sites are parotid gland, sinus, nasal septum and cleft palate. PA is an uncommon benign type of tumor occurring in the breast, and there are few reports of cases in Asia.
An 84-year-old woman found a mass in the upper outer quadrant of the right breast > 1 year ago. The patient underwent a right breast lumpectomy and sentinel lymph node biopsy. The pathological diagnosis was PA in the upper outer quadrant of the right breast, and the malignant component was malignant adenomyoepithelioma. The postoperative course was uneventful, and no chemotherapy was administered. At 18 mo of follow-up, the patient is alive and well, with no evidence of recurrent disease.
Patients with breast PA should first undergo extended excision of breast masses followed by pathological examination. If malignancy is confirmed or the surgical margin is positive, modified radical mastectomy should be performed.
多形性腺瘤（PA）是涎腺肿瘤最常见的类型，其常见部位为腮腺、鼻窦、鼻中隔和腭裂。PA是一种罕见的发生于乳腺的良性肿瘤类型，亚洲地区的病例报道较少。
一名84岁女性于1年多前发现右乳外上象限有一肿块。患者接受了右乳肿块切除术及前哨淋巴结活检。病理诊断为右乳外上象限PA，恶性成分是恶性腺肌上皮瘤。术后恢复顺利，未进行化疗。随访18个月时，患者健在，无疾病复发迹象。
乳腺PA患者应首先进行乳腺肿块扩大切除，随后进行病理检查。如果确诊为恶性或手术切缘阳性，则应行改良根治性乳房切除术。
